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PYCARD 抗体 (AA 1-120)

PYCARD 适用: 人 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 1C3D3 unconjugated
产品编号 ABIN5542580
发货至: 中国
  • 抗原 See all PYCARD 抗体
    PYCARD (PYD and CARD Domain Containing (PYCARD))
    抗原表位
    • 10
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-120
    适用
    • 56
    • 10
    • 9
    • 1
    • 1
    • 1
    宿主
    • 48
    • 6
    • 3
    小鼠
    克隆类型
    • 47
    • 10
    单克隆
    标记
    • 32
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This PYCARD antibody is un-conjugated
    应用范围
    • 39
    • 22
    • 14
    • 13
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    原理
    PYCARD Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human PYCARD (AA: 1-120) expressed in E. Coli.
    克隆位点
    1C3D3
    亚型
    IgG1
    Top Product
    Discover our top product PYCARD Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    PYCARD (PYD and CARD Domain Containing (PYCARD))
    别名
    PYCARD (PYCARD 产品)
    别名
    ASC antibody, CARD5 antibody, TMS antibody, TMS-1 antibody, TMS1 antibody, 9130417A21Rik antibody, Asc antibody, TNS1 antibody, masc antibody, asc1 antibody, zAsc antibody, zgc:109874 antibody, PYD and CARD domain containing antibody, PYCARD antibody, Pycard antibody, pycard antibody
    背景

    Description: This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm, however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.

    Aliases: ASC, TMS, TMS1, CARD5, TMS-1

    分子量
    21.6kDa
    基因ID
    29108
    HGNC
    29108
    UniProt
    Q9ULZ3
    途径
    Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation, Inflammasome
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