ATG5 抗体
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- 抗原 See all ATG5 抗体
- ATG5 (ATG5 Autophagy Related 5 (ATG5))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ATG5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 原理
- ATG5 Antibody
- 序列
- Synthesize d peptide of human ATG5 (AA: MTDDKDVLRD VWFGRIc).
- 纯化方法
- Purified antibody
- 免疫原
- Synthesized peptide of human ATG5 (AA: MTDDKDVLRDVWFGRIc).
- 克隆位点
- 8E8G6
- 亚型
- IgG2a
- Top Product
- Discover our top product ATG5 Primary Antibody
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anti-ATG5 Autophagy Related 5 (ATG5) (AA 101-200) antibody
ATG5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-ATG5 Autophagy Related 5 (ATG5) (AA 1-275) antibodyATG5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATG5 Autophagy Related 5 (ATG5) (AA 209-238), (C-Term) antibodyATG5 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB7547 unconjugated
anti-ATG5 Autophagy Related 5 (ATG5) (AA 144-275) antibodyATG5 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 3C7A8 unconjugated
anti-ATG5 Autophagy Related 5 (ATG5) (AA 176-275) antibodyATG5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G11 unconjugated
anti-ATG5 Autophagy Related 5 (ATG5) (AA 1-119) antibodyATG5 适用: 人 WB, ELISA, IHC, Coat, StM 宿主: 小鼠 Monoclonal ATG5-2101 unconjugated
anti-ATG5 Autophagy Related 5 (ATG5) (AA 1-30) antibodyATG5 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-ATG5 Autophagy Related 5 (ATG5) (AA 1-30), (N-Term) antibodyATG5 适用: 人, 小鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-ATG5 Autophagy Related 5 (ATG5) (C-Term) antibodyATG5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-ATG5 Autophagy Related 5 (ATG5) (AA 28-275) antibodyATG5 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- ATG5 (ATG5 Autophagy Related 5 (ATG5))
- 别名
- ATG5 (ATG5 产品)
- 别名
- APG5 antibody, APG5-LIKE antibody, APG5L antibody, ASP antibody, hAPG5 antibody, ATG5 antibody, CG1643 antibody, DmAtg5 antibody, Dmel\\CG1643 antibody, atg5 antibody, 2010107M05Rik antibody, 3110067M24Rik antibody, AW319544 antibody, Apg5l antibody, Atg5l antibody, C88337 antibody, Paddy antibody, apg5l antibody, zgc:100934 antibody, ATATG5 antibody, AUTOPHAGY 5 antibody, MKP11.20 antibody, MKP11_20 antibody, autophagy related 5 antibody, Autophagy-related 5 antibody, ATG5 autophagy related 5 homolog (S. cerevisiae) antibody, autophagy related 5 L homeolog antibody, similar to S. cerevisiae ATG5 (YPL149W) which nucleates preautophagosome formation as a conjugate with Atg12 antibody, autophagy protein Apg5 family antibody, ATG5 antibody, Atg5 antibody, atg5 antibody, atg5.L antibody, APG5 antibody
- 背景
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Description: ATG5 involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating
system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential
for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8
family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after
oxidative damage, and in subsequent cellular longevity. The ATG12-ATG5 conjugate also negatively regulates the
innate antiviral immune response by blocking the type I IFN production pathway through direct association with
RARRES3 and MAVS. Also plays a role in translation or delivery of incoming viral RNA to the translation
apparatus. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T
lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II.
Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte
differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation
of IFT20 via the autophagic pathwayAliases: ASP, APG5, APG5L, hAPG5, APG5-LIKE
- 分子量
- 32.4kDa
- 基因ID
- 9474
- HGNC
- 9474
- UniProt
- Q9H1Y0
- 途径
- Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy
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