TCL1A 抗体 (AA 10-104)
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- 抗原 See all TCL1A 抗体
- TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))
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抗原表位
- AA 10-104
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TCL1A antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS)
- 原理
- TCL1A Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human TCL1A (AA: 10-104) expressed in E. Coli.
- 克隆位点
- 2E3A5
- 亚型
- IgG1
- Top Product
- Discover our top product TCL1A Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))
- 别名
- TCL1A (TCL1A 产品)
- 别名
- TCL1A antibody, Tcl1a antibody, TCL1 antibody, Tcl1 antibody, T-cell leukemia/lymphoma 1A antibody, T cell lymphoma breakpoint 1 antibody, TCL1A antibody, Tcl1 antibody, Tcl1a antibody
- 背景
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Description: Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).
Aliases: TCL1
- 分子量
- 13.5kDa
- 基因ID
- 8115
- HGNC
- 8115
- UniProt
- P56279
- 途径
- Stem Cell Maintenance
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