DNMT3B 抗体 (AA 1-150)
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- 抗原 See all DNMT3B 抗体
- DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))
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抗原表位
- AA 1-150
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This DNMT3B antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
- 原理
- DNMT3B Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human DNMT3B (AA: 1-150) expressed in E. Coli.
- 克隆位点
- 7E5E9C1
- 亚型
- IgG1
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))
- 别名
- DNMT3B (DNMT3B 产品)
- 别名
- DNMT3B antibody, LOC100218113 antibody, ICF antibody, ICF1 antibody, M.HsaIIIB antibody, MmuIIIB antibody, cb91 antibody, dnmt3bl antibody, dnmt7 antibody, sb:cb91 antibody, wu:fb16h07 antibody, DNA methyltransferase 3 beta antibody, DNA methyltransferase 3B antibody, DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a antibody, DNMT3B antibody, Dnmt3b antibody, dnmt3b antibody, dnmt3ba antibody
- 背景
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Description: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.
Aliases: ICF, ICF1, M.HsaIIIB
- 分子量
- 95.8kDa
- 基因ID
- 1789
- HGNC
- 1789
- UniProt
- Q9UBC3
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