DNMT3L 抗体 (AA 147-386)
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- 抗原 See all DNMT3L (TRDMT1) 抗体
- DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))
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抗原表位
- AA 147-386
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This DNMT3L antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS)
- 原理
- DNMT3L Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human DNMT3L (AA: 147-386) expressed in E. Coli.
- 克隆位点
- 2D10H11
- 亚型
- IgG1
- Top Product
- Discover our top product TRDMT1 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- DNMT3L (TRDMT1) (DNA (Cytosine-5-)-Methyltransferase 3 Like (TRDMT1))
- 别名
- DNMT3L (TRDMT1 产品)
- 别名
- DNMT3L antibody, D6Ertd14e antibody, ecat7 antibody, DNA methyltransferase 3 like antibody, DNA (cytosine-5-)-methyltransferase 3-like antibody, DNMT3L antibody, Dnmt3l antibody
- 背景
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CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- 分子量
- 43.6kDa
- 基因ID
- 29947
- HGNC
- 29947
- UniProt
- Q9UJW3
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