DDX3X 抗体 (AA 518-661)
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- 抗原 See all DDX3X 抗体
- DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))
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抗原表位
- AA 518-661
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This DDX3X antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
- 原理
- DDX3X Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human DDX3X (AA: 518-661) expressed in E. Coli.
- 克隆位点
- 3B9E3
- 亚型
- IgG2a
- Top Product
- Discover our top product DDX3X Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- DDX3X (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 3, X-Linked (DDX3X))
- 别名
- DDX3X (DDX3X 产品)
- 别名
- DBX antibody, DDX14 antibody, DDX3 antibody, HLP2 antibody, D1Pas1-rs2 antibody, Ddx3 antibody, Fin14 antibody, An3 antibody, pl10 antibody, DDX3X antibody, DEAD-box helicase 3, X-linked antibody, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked antibody, DEAD-box helicase 3, X-linked L homeolog antibody, DDX3X antibody, Ddx3x antibody, ddx3x.L antibody, ddx3x antibody
- 背景
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Description: The protein encoded by this gene is a member of the large DEAD-box protein family, that is defined by the presence of the conserved Asp-Glu-Ala-Asp (DEAD) motif, and has ATP-dependent RNA helicase activity. This protein has been reported to display a high level of RNA-independent ATPase activity, and unlike most DEAD-box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export. In the cytoplasm, this protein is thought to be involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been implicated in tumorigenesis. This gene has a paralog located in the nonrecombining region of the Y chromosome. Pseudogenes sharing similarity to both this gene and the DDX3Y paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants.
Aliases: DBX, DDX3, HLP2, DDX14, CAP-Rf
- 分子量
- 73.2kDa
- 基因ID
- 1654
- HGNC
- 1654
- UniProt
- O00571
- 途径
- Ribonucleoprotein Complex Subunit Organization, Positive Regulation of Endopeptidase Activity, Negative Regulation of intrinsic apoptotic Signaling, Ribosome Assembly
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