BAD 抗体 (AA 1-168)
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- 抗原 See all BAD 抗体
- BAD (BCL2-Associated Agonist of Cell Death (BAD))
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抗原表位
- AA 1-168
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This BAD antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Flow Cytometry (FACS)
- 原理
- BAD Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human BAD (AA: FULL(1-168)) expressed in E. Coli.
- 克隆位点
- 1G5B3
- 亚型
- IgG1
- Top Product
- Discover our top product BAD Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- BAD (BCL2-Associated Agonist of Cell Death (BAD))
- 别名
- BAD (BAD 产品)
- 别名
- bad antibody, fa01b12 antibody, wu:fa01b12 antibody, wu:fa96d04 antibody, BAD antibody, BBC2 antibody, BCL2L8 antibody, AI325008 antibody, Bbc2 antibody, BCL2-associated agonist of cell death b antibody, BCL2 associated agonist of cell death antibody, BCL2-associated agonist of cell death antibody, badb antibody, BAD antibody, Bad antibody
- 背景
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Description: The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Aliases: BBC2, BCL2L8
- 分子量
- 18.4kDa
- 基因ID
- 572
- HGNC
- 572
- UniProt
- Q92934
- 途径
- MAPK Pathway, PI3K-Akt Signaling, RTK signaling, Apoptosis, Fc-epsilon Receptor Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
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