MECP2 抗体 (AA 7-148)
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- 抗原 See all MECP2 抗体
- MECP2 (Methyl CpG Binding Protein 2 (MECP2))
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抗原表位
- AA 7-148
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MECP2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of human MECP2 (AA: 7-148) expressed in E. coli.
- 克隆位点
- 8H4A5B9
- 亚型
- IgG1
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- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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- 抗原
- MECP2 (Methyl CpG Binding Protein 2 (MECP2))
- 别名
- MECP2 (MECP2 产品)
- 别名
- AUTSX3 antibody, MRX16 antibody, MRX79 antibody, MRXS13 antibody, MRXSL antibody, PPMX antibody, RS antibody, RTS antibody, RTT antibody, 1500041B07Rik antibody, BB130002 antibody, D630021H01Rik antibody, Mbd5 antibody, WBP10 antibody, wu:fk96a04 antibody, zgc:111857 antibody, methyl-CpG binding protein 2 antibody, methyl CpG binding protein 2 antibody, methyl-CpG binding protein 2 S homeolog antibody, MECP2 antibody, Mecp2 antibody, mecp2 antibody, mecp2.S antibody
- 背景
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Description: DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.,
Aliases: RS, RTS, RTT, PPMX, MRX16, MRX79, MRXSL, AUTSX3, MRXS13
- 分子量
- 52.4 kDa
- 基因ID
- 4204
- HGNC
- 4204
- 途径
- Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane
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