UCP2 抗体 (AA 1-309)
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- 抗原 See all UCP2 抗体
- UCP2 (Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2))
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抗原表位
- AA 1-309
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This UCP2 antibody is un-conjugated
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应用范围
- ELISA
- 原理
- UCP2 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human UCP2 (AA: 1-309) expressed in E. Coli.
- 克隆位点
- 6C8B3
- 亚型
- IgG1
- Top Product
- Discover our top product UCP2 Primary Antibody
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- 应用备注
- ELISA: 1/10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- UCP2 (Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2))
- 别名
- UCP2 (UCP2 产品)
- 别名
- UCP2 antibody, DKFZp470P1633 antibody, ucp2 antibody, MGC53319 antibody, MGC75881 antibody, cb74 antibody, ATUCP2 antibody, K19M22.21 antibody, K19M22_21 antibody, uncoupling protein 2 antibody, BMIQ4 antibody, SLC25A8 antibody, UCPH antibody, Slc25a8 antibody, mitochondrial uncoupling protein 2 antibody, uncoupling protein 2 antibody, uncoupling protein 2 (mitochondrial, proton carrier) L homeolog antibody, uncoupling protein 2 (mitochondrial, proton carrier) antibody, uncoupling protein 1 antibody, PTRG_09289 antibody, UCP2 antibody, LOC100282746 antibody, ucp2.L antibody, ucp2 antibody, ucp1 antibody, Ucp2 antibody
- 背景
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Description: Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'.
Aliases: UCPH, BMIQ4, SLC25A8
- 分子量
- 33.2kDa
- 基因ID
- 7351
- HGNC
- 7351
- UniProt
- P55851
- 途径
- Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Proton Transport
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