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SMAD1 抗体 (AA 1-110)

SMAD1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E12H10 unconjugated
产品编号 ABIN5542387
发货至: 中国
  • 抗原 See all SMAD1 抗体
    SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))
    抗原表位
    • 23
    • 23
    • 23
    • 15
    • 15
    • 13
    • 11
    • 9
    • 8
    • 6
    • 6
    • 5
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    • 3
    • 3
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    • 2
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    • 2
    • 2
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-110
    适用
    • 209
    • 129
    • 93
    • 9
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
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    • 3
    • 1
    宿主
    • 207
    • 17
    小鼠
    克隆类型
    • 201
    • 24
    单克隆
    标记
    • 101
    • 19
    • 13
    • 8
    • 6
    • 6
    • 6
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    • 4
    • 4
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    • 4
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    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    This SMAD1 antibody is un-conjugated
    应用范围
    • 173
    • 89
    • 53
    • 52
    • 43
    • 32
    • 21
    • 17
    • 12
    • 12
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    原理
    SMAD1 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human SMAD1 (AA: 1-110) expressed in E. Coli.
    克隆位点
    4E12H10
    亚型
    IgG1
    Top Product
    Discover our top product SMAD1 Primary Antibody
  • 应用备注
    ELISA: 1/10000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))
    别名
    SMAD1 (SMAD1 产品)
    别名
    MLP antibody, Xmad1 antibody, Xsmad1 antibody, bsp1 antibody, jv4-1 antibody, jv41 antibody, madh1 antibody, madr1 antibody, smad-1 antibody, MADH1 antibody, fb39h09 antibody, wu:fb39h09 antibody, wu:fb97e04 antibody, 2/23 antibody, CG12399 antibody, Dmel\\CG12399 antibody, E(zen)2 antibody, En(vvl) antibody, MAD antibody, Mat antibody, P-Mad antibody, P-mad antibody, PMad antibody, Smad antibody, Smad1 antibody, apg antibody, c28 antibody, dMAD antibody, dMad antibody, l(2)K00237 antibody, l(2)k00237 antibody, mad antibody, p-Mad antibody, pMAD antibody, pMad antibody, pSmad antibody, BSP-1 antibody, BSP1 antibody, JV4-1 antibody, JV41 antibody, MADR1 antibody, AI528653 antibody, Madh1 antibody, Madr1 antibody, Mlp1 antibody, MusMLP antibody, smad1 antibody, xmad antibody, SMAD family member 1 antibody, Mothers against dpp antibody, SMAD family member 1 L homeolog antibody, smad1 antibody, SMAD1 antibody, Mad antibody, Smad1 antibody, smad1.L antibody
    背景

    Description: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed.

    Aliases: BSP1, JV41, BSP-1, JV4-1, MADH1, MADR1

    分子量
    52kDa
    基因ID
    4086
    HGNC
    4086
    UniProt
    Q15797
    途径
    Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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