PKN1 抗体 (AA 442-620)
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- 抗原 See all PKN1 抗体
- PKN1 (Protein Kinase N1 (PKN1))
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抗原表位
- AA 442-620
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PKN1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
- 原理
- PKN1 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human PKN1 (AA: 442-620) expressed in E. Coli.
- 克隆位点
- 4H10B1
- 亚型
- IgG2b
- Top Product
- Discover our top product PKN1 Primary Antibody
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- 应用备注
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- 抗原
- PKN1 (Protein Kinase N1 (PKN1))
- 别名
- PKN1 (PKN1 产品)
- 背景
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Description: The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Aliases: DBK, PKN, PAK1, PRK1, PAK-1, PRKCL1, PKN-ALPHA
- 分子量
- 104kDa
- 基因ID
- 5585
- HGNC
- 5585
- UniProt
- Q16512
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