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RAB8A 抗体 (AA 68-207)

RAB8A 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7G8B11 unconjugated
产品编号 ABIN5542342
发货至: 中国
  • 抗原 See all RAB8A 抗体
    RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))
    抗原表位
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 68-207
    适用
    • 34
    • 12
    • 11
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 20
    • 10
    • 3
    小鼠
    克隆类型
    • 24
    • 10
    单克隆
    标记
    • 20
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This RAB8A antibody is un-conjugated
    应用范围
    • 18
    • 7
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS)
    原理
    Rab8 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human Rab8 (AA: 68-207) expressed in E. Coli.
    克隆位点
    7G8B11
    亚型
    IgG2b
    Top Product
    Discover our top product RAB8A Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))
    别名
    Rab8 (RAB8A 产品)
    背景

    Description: The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97 % , 96 %, and 51 % similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.

    Aliases: MEL, RAB8A

    分子量
    23.7kDa
    基因ID
    4218
    HGNC
    4218
    UniProt
    P61006
    途径
    M Phase, Regulation of long-term Neuronal Synaptic Plasticity, SARS-CoV-2 Protein Interactome
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