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LDLR 抗体 (AA 22-150)

LDLR 适用: 人 ELISA, FACS, IHC 宿主: 小鼠 Monoclonal 1B10H10 unconjugated
产品编号 ABIN5542334
发货至: 中国
  • 抗原 See all LDLR 抗体
    LDLR (Low Density Lipoprotein Receptor (LDLR))
    抗原表位
    • 16
    • 8
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 22-150
    适用
    • 80
    • 45
    • 32
    • 17
    • 16
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 69
    • 12
    • 5
    小鼠
    克隆类型
    • 68
    • 18
    单克隆
    标记
    • 44
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LDLR antibody is un-conjugated
    应用范围
    • 59
    • 34
    • 25
    • 18
    • 13
    • 8
    • 8
    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC)
    原理
    LDLR Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human LDLR (AA: 22-150) expressed in E. Coli.
    克隆位点
    1B10H10
    亚型
    IgG1
    Top Product
    Discover our top product LDLR Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    LDLR (Low Density Lipoprotein Receptor (LDLR))
    别名
    LDLR (LDLR 产品)
    别名
    FH antibody, FHC antibody, LDLCQ2 antibody, Hlb301 antibody, LDLRA antibody, LDLA antibody, LDL receptor-2 antibody, fhc antibody, ldlcq2 antibody, ldlr antibody, ldlr2-a antibody, LDL receptor 1 antibody, ldlr-a antibody, ldlr-b antibody, low density lipoprotein receptor antibody, low density lipoprotein receptor a antibody, low density lipoprotein receptor S homeolog antibody, low density lipoprotein receptor L homeolog antibody, LDLR antibody, Ldlr antibody, ldlra antibody, ldlr.S antibody, ldlr.L antibody
    背景

    Description: The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.r

    Aliases: FH, FHC, LDLCQ2

    分子量
    95.4kDa
    基因ID
    3949
    HGNC
    3949
    UniProt
    P01130
    途径
    Hepatitis C, Lipid Metabolism
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