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FGFR3 抗体 (AA 529-694)

FGFR3 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1E3F9 unconjugated
产品编号 ABIN5542299
发货至: 中国
  • 抗原 See all FGFR3 抗体
    FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))
    抗原表位
    • 22
    • 15
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 529-694
    适用
    • 116
    • 56
    • 48
    • 4
    • 1
    • 1
    • 1
    宿主
    • 109
    • 6
    • 1
    • 1
    小鼠
    克隆类型
    • 98
    • 19
    单克隆
    标记
    • 39
    • 12
    • 8
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This FGFR3 antibody is un-conjugated
    应用范围
    • 79
    • 42
    • 39
    • 13
    • 13
    • 11
    • 10
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    ELISA
    原理
    FGFR3 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human FGFR3 (AA: 529-694) expressed in E. Coli.
    克隆位点
    1E3F9
    亚型
    IgG2a
    Top Product
    Discover our top product FGFR3 Primary Antibody
  • 应用备注
    ELISA: 1/10000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))
    别名
    FGFR3 (FGFR3 产品)
    别名
    FGFR3 antibody, LOC100034114 antibody, ACH antibody, CD333 antibody, CEK2 antibody, HSFGFR3EX antibody, JTK4 antibody, FR3 antibody, Fgfr-3 antibody, Flg-2 antibody, HBGFR antibody, Mfr3 antibody, sam3 antibody, fc27h01 antibody, wu:fc27h01 antibody, fibroblast growth factor receptor 3 antibody, fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) S homeolog antibody, FGFR3 antibody, fgfr3.S antibody, Fgfr3 antibody, fgfr3 antibody
    背景

    Description: This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described.

    Aliases: ACH, CEK2, JTK4, CD333, HSFGFR3EX

    分子量
    87.7kDa
    基因ID
    2261
    HGNC
    2261
    UniProt
    P22607
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Growth Factor Binding
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