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BIN1 抗体 (AA 189-398)

BIN1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3B6A4 unconjugated
产品编号 ABIN5542281
发货至: 中国
  • 抗原 See all BIN1 抗体
    BIN1 (Bridging Integrator 1 (BIN1))
    抗原表位
    • 8
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 189-398
    适用
    • 47
    • 24
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 34
    • 12
    • 1
    小鼠
    克隆类型
    • 36
    • 11
    单克隆
    标记
    • 33
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BIN1 antibody is un-conjugated
    应用范围
    • 35
    • 21
    • 19
    • 9
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    原理
    BIN1 Antibody
    纯化方法
    Purified antibody
    免疫原
    Purified recombinant fragment of human BIN1 (AA: 189-398) expressed in E. Coli.
    克隆位点
    3B6A4
    亚型
    IgG2b
    Top Product
    Discover our top product BIN1 Primary Antibody
  • 应用备注

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • 抗原
    BIN1 (Bridging Integrator 1 (BIN1))
    别名
    BIN1 (BIN1 产品)
    别名
    bin1 antibody, MGC53185 antibody, amph2 antibody, amphl antibody, sh3p9 antibody, MGC76187 antibody, cb57 antibody, zgc:86701 antibody, BIN1 antibody, AMPH2 antibody, AMPHL antibody, SH3P9 antibody, ALP-1 antibody, Amphl antibody, BRAMP-2 antibody, bridging integrator 1 antibody, bridging integrator 1 S homeolog antibody, bridging integrator 1b antibody, BIN1 antibody, bin1.S antibody, bin1 antibody, bin1b antibody, Bin1 antibody
    背景

    Description: This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.

    Aliases: AMPH2, AMPHL, SH3P9

    分子量
    64.7kDa
    基因ID
    274
    HGNC
    274
    UniProt
    O00499
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