-
- 抗原 See all CSF2RA 抗体
- CSF2RA (Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA))
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This CSF2RA antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- This antibody recognizes Human CD116, the GM-CSF receptor alpha subunit (approx. 80 kDa) expressed e.g. by neutrophils, eosinophils, monocytes and macrophages.
- 纯化方法
- Affinity Chromatography on Protein A
- 免疫原
- CD116-transfected COS cells
- 克隆位点
- 4H1
- 亚型
- IgG1
- Top Product
- Discover our top product CSF2RA Primary Antibody
-
-
- 应用备注
- Flow Cytometry. Immunoprecipitation. Western blot. Immunohistochemistry on Frozen Sections.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- 95 % by SDS-PAGE) Purified
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
- 有效期
- 12 months
-
-
Decreased Renal Expression of H(+)-ATPase and Pendrin in a Patient with Distal Renal Tubular Acidosis Associated with Sjögren's Syndrome." in: Internal medicine (Tokyo, Japan), Vol. 54, Issue 22, pp. 2899-904, (2016) (PubMed).
: "Significance of low level infliximab in the absence of anti-infliximab antibodies." in: World journal of gastroenterology, Vol. 21, Issue 6, pp. 1907-14, (2015) (PubMed).
: "Identification of a subnuclear body involved in sequence-specific cytokine RNA processing." in: Nature communications, Vol. 6, pp. 5791, (2015) (PubMed).
: "Peripheral monocyte functions and activation in patients with quiescent Crohn's disease." in: PLoS ONE, Vol. 8, Issue 4, pp. e62761, (2013) (PubMed).
: "Therapeutic effect of human iPS-cell-derived myeloid cells expressing IFN-? against peritoneally disseminated cancer in xenograft models." in: PLoS ONE, Vol. 8, Issue 6, pp. e67567, (2013) (PubMed).
: "Multi-parameter determination of TNF?, PCT and CRP for point-of-care testing." in: The Analyst, Vol. 136, Issue 4, pp. 692-5, (2011) (PubMed).
: "IL-15 trans-presentation promotes human NK cell development and differentiation in vivo." in: The Journal of experimental medicine, Vol. 206, Issue 1, pp. 25-34, (2009) (PubMed).
: "The involvement of IL-23 and the Th17 pathway in periodontitis." in: Journal of dental research, Vol. 88, Issue 7, pp. 633-8, (2009) (PubMed).
: "CRP determination based on a novel magnetic biosensor." in: Biosensors & bioelectronics, Vol. 22, Issue 6, pp. 973-9, (2007) (PubMed).
: "p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy." in: The Journal of biological chemistry, Vol. 282, Issue 33, pp. 24131-45, (2007) (PubMed).
: "
-
Decreased Renal Expression of H(+)-ATPase and Pendrin in a Patient with Distal Renal Tubular Acidosis Associated with Sjögren's Syndrome." in: Internal medicine (Tokyo, Japan), Vol. 54, Issue 22, pp. 2899-904, (2016) (PubMed).
-
- 抗原
- CSF2RA (Colony Stimulating Factor 2 Receptor, Alpha, Low-Affinity (Granulocyte-Macrophage) (CSF2RA))
- 别名
- cd116,csf2ra (CSF2RA 产品)
- 别名
- CD116 antibody, CDw116 antibody, CSF2R antibody, CSF2RAX antibody, CSF2RAY antibody, CSF2RX antibody, CSF2RY antibody, GM-CSF-R-alpha antibody, GMCSFR antibody, GMR antibody, SMDP4 antibody, Csfgmra antibody, GM-CSF-Ra antibody, GM-CSFR antibody, colony stimulating factor 2 receptor, alpha antibody, colony stimulating factor 2 receptor alpha subunit antibody, colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) antibody, CSF2RA antibody, Csf2ra antibody
- 背景
- CD116 (GM-CSF R alpha) is the low affinity receptor for granulocyte-macrophage colony-stimulating factor (GM-CSF). CD116 heterodimerizes with CD131, the common beta chain subunit shared with IL-3 and IL5 receptors, to form the high affinity GM-CSF receptor. CD116 is expressed by myeloid cells including macrophages, neutrophils, eosinophils, dendritic cells, and their precursors, as well as on endothelial cells. It is being used as a specific marker of myeloid leukemias.
- UniProt
- P15509
- 途径
- JAK/STAT Signaling
-