Staphylococcus Aureus Enterotoxin Type B 抗体
适用: Staphylococcus aureus
EIA
宿主: 小鼠
Monoclonal
SEB
unconjugated
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- 抗原 See all Staphylococcus Aureus Enterotoxin Type B products
- Staphylococcus Aureus Enterotoxin Type B
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适用
- Staphylococcus aureus
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Staphylococcus Aureus Enterotoxin Type B antibody is un-conjugated
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应用范围
- Enzyme Immunoassay (EIA)
- 特异性
- Staphylococcal Enterotoxin B (SEB).
- 纯化方法
- Affinity Chromatography on Protein G
- 免疫原
- SEB purified from Staphylococcus aureus.
- 克隆位点
- SEB
- 亚型
- IgG1
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- 应用备注
- ELISA. This Staphylococcal Enterotoxin B (Clone SEB) as a superantigen for T-lymphocytes is a potential targeting antigen in cancer immunotherapy. It has been suggested that monoclonal antibody to SEB has been useful in immunotherapy research.
- 限制
- 仅限研究用
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- 缓冲液
- 0.01M PBS, pH 7.2 without preservatives
- 储存液
- Without preservative
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
- 有效期
- 12 months
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- 抗原
- Staphylococcus Aureus Enterotoxin Type B
- 别名
- staphylococcus aureus enterotoxin b (Staphylococcus Aureus Enterotoxin Type B 产品)
- 背景
- Staphylococcal enterotoxin B (SEB) is an enterotoxin secreted by Staphylococcus aureus. The bacterium thrives on meet, baking and dairy products and also colonizes in host nasal passageway. Ingestion of SEB contaminated food is the common cause of "food poisoning", manifested by flu-like symptoms, vomiting, diarrhea and intestinal cramps. In severe cases, SEB can cause respiratory failure and systemic toxic shock. These symptoms are the results of increased membrane permeability and abnormal activation of Tlymphocytes by SEB. SEB acts as a superantigen by binding directly to major histocompatibility complex class II (MHCII) on antigen presenting cells, thus, causing massive CD4 and CD8 Tcells activation and cytokine production. If unchecked, the process can result in systemic organ failure and death.
- UniProt
- P01552
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