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Rituximab 抗体 (HRP)

EIA 宿主: 大鼠 Monoclonal MB2 A4 HRP
产品编号 ABIN5541687
发货至: 中国
  • 抗原 See all Rituximab products
    Rituximab
    适用
    请咨询
    宿主
    • 3
    • 2
    大鼠
    克隆类型
    • 5
    单克隆
    标记
    • 3
    • 2
    This Rituximab antibody is conjugated to HRP
    应用范围
    • 3
    • 2
    • 1
    • 1
    Enzyme Immunoassay (EIA)
    特异性
    This antibody specifically recognises the idiotypic determinants expressed by the Rituximab humanised monoclonal antibody. This antibody does not recognise other CD20 antibodies. It has been used to detect Rituximab bound to the surface of the Raji B cell line, however detection of Rituximab bound 'in vivo' to B-CLL cells has not been demonstrated. It is possible that complement deposition on Rituximab opsonised cells inhibits binding of the anti-Rituximab antibody to cell bound Rituximab (3). Clone MB2A4 has been used in ELISA assays to monitor the levels of rituximab in patient serum following therapy (4,5).
    纯化方法
    Affinity chromatography on Protein G
    免疫原
    F(ab)2 fragment of Rituximab
    克隆位点
    MB2 A4
    亚型
    IgG2a
  • 应用备注
    ELISA: 1/20000-1/20000.
    限制
    仅限研究用
  • 状态
    Liquid
    储存条件
    4 °C
    储存方法
    Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    Rituximab
    Abstract
    Rituximab 产品
    物质类
    Antibody
    背景
    Rituximab is a therapeutic reagent directed against the human CD20 cell surface antigen.
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