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LARGE 抗体 (AA 35-142)

LARGE 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal LARGE-02 unconjugated
产品编号 ABIN5541530
发货至: 中国
  • 抗原 See all LARGE 抗体
    LARGE (Like-Glycosyltransferase (LARGE))
    抗原表位
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 35-142
    适用
    • 9
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    宿主
    • 6
    • 2
    • 1
    小鼠
    克隆类型
    • 8
    • 1
    单克隆
    标记
    • 8
    • 1
    This LARGE antibody is un-conjugated
    应用范围
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    特异性
    This antibody recognizes human LARGE1, a glycosyltransferase localizing mainly to the Golgi apparatus. Crossreactivity with LARGE2 was not determined.
    纯化方法
    Protein-A affinity chromatography (> 95% pure by SDS-PAGE)
    免疫原
    Recombinant fragment of human LARGE1 (amino acids 35-142)
    克隆位点
    LARGE-02
    亚型
    IgG2b
    Top Product
    Discover our top product LARGE Primary Antibody
  • 应用备注
    Flow cytometry. Western blot.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    95 % pure by SDS-PAGE) Buffer System: Phosphate buffered saline (PBS) Preservatives: 15 mM sodium azide, approx. pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    LARGE (Like-Glycosyltransferase (LARGE))
    别名
    large (LARGE 产品)
    别名
    gyltl1b antibody, gyltl1b-b antibody, mdc1d antibody, MDC1D antibody, MDDGA6 antibody, MDDGB6 antibody, BPFD36 antibody, Gyltl1a antibody, Mbp-1 antibody, Mbp1 antibody, enr antibody, fg antibody, froggy antibody, mKIAA0609 antibody, myd antibody, NV15834 antibody, DKFZp459G0120 antibody, LARGE xylosyl- and glucuronyltransferase 1 L homeolog antibody, LARGE xylosyl- and glucuronyltransferase 1 antibody, glycosyltransferase-like protein LARGE1 antibody, like-glycosyltransferase antibody, large1.L antibody, LARGE1 antibody, Large1 antibody, large1 antibody, LOC100118066 antibody, LARGE antibody, Large antibody
    背景
    LARGE1 serves as a glycosyltransferase which participates in glycosylation of the muscle membrane protein alpha-dystroglycan. Mutations of LARGE1 lead to hypoglycosylation of alpha-dystroglycan and cause congenital muscular dystrophy (MDC1D) associated with severe mental retardation. Altered alpha-dystroglycan glycosylation may also play a role in cancer, as hypoglycosylation of the protein and loss of laminin binding have been demonstrated in invasive carcinoma cells.
    UniProt
    O95461
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