LARGE 抗体 (AA 35-142)
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- 抗原 See all LARGE 抗体
- LARGE (Like-Glycosyltransferase (LARGE))
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抗原表位
- AA 35-142
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This LARGE antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS)
- 特异性
- This antibody recognizes human LARGE1, a glycosyltransferase localizing mainly to the Golgi apparatus. Crossreactivity with LARGE2 was not determined.
- 纯化方法
- Protein-A affinity chromatography (> 95% pure by SDS-PAGE)
- 免疫原
- Recombinant fragment of human LARGE1 (amino acids 35-142)
- 克隆位点
- LARGE-02
- 亚型
- IgG2b
- Top Product
- Discover our top product LARGE Primary Antibody
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anti-Like-Glycosyltransferase (LARGE) (AA 25-178) antibody
LARGE 适用: 人 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Like-Glycosyltransferase (LARGE) (AA 365-398) antibodyLARGE 适用: 人 WB 宿主: 兔 Polyclonal RB55257 unconjugated
anti-Like-Glycosyltransferase (LARGE) (AA 683-732) antibodyLARGE 适用: 人, 小鼠, Cow, 犬, 马, 兔, 大鼠, 斑马鱼, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Like-Glycosyltransferase (LARGE) (AA 421-433) antibodyVerified LARGE 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Like-Glycosyltransferase (LARGE) (Middle Region) antibodyLARGE 适用: 人, 小鼠, Cow, 犬, 马, 兔, 大鼠, 斑马鱼, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Flow cytometry. Western blot.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 95 % pure by SDS-PAGE) Buffer System: Phosphate buffered saline (PBS) Preservatives: 15 mM sodium azide, approx. pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
- 有效期
- 12 months
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- 抗原
- LARGE (Like-Glycosyltransferase (LARGE))
- 别名
- large (LARGE 产品)
- 别名
- gyltl1b antibody, gyltl1b-b antibody, mdc1d antibody, MDC1D antibody, MDDGA6 antibody, MDDGB6 antibody, BPFD36 antibody, Gyltl1a antibody, Mbp-1 antibody, Mbp1 antibody, enr antibody, fg antibody, froggy antibody, mKIAA0609 antibody, myd antibody, NV15834 antibody, DKFZp459G0120 antibody, LARGE xylosyl- and glucuronyltransferase 1 L homeolog antibody, LARGE xylosyl- and glucuronyltransferase 1 antibody, glycosyltransferase-like protein LARGE1 antibody, like-glycosyltransferase antibody, large1.L antibody, LARGE1 antibody, Large1 antibody, large1 antibody, LOC100118066 antibody, LARGE antibody, Large antibody
- 背景
- LARGE1 serves as a glycosyltransferase which participates in glycosylation of the muscle membrane protein alpha-dystroglycan. Mutations of LARGE1 lead to hypoglycosylation of alpha-dystroglycan and cause congenital muscular dystrophy (MDC1D) associated with severe mental retardation. Altered alpha-dystroglycan glycosylation may also play a role in cancer, as hypoglycosylation of the protein and loss of laminin binding have been demonstrated in invasive carcinoma cells.
- UniProt
- O95461
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