TEP1 抗体 (N-Term)
TEP1
适用: 人, 小鼠, 大鼠
WB, IHC (p)
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all TEP1 抗体
- TEP1 (Telomerase-Associated Protein 1 (TEP1))
- 抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TEP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- Species: Human, Mouse and Rat.
- 纯化方法
- Immunoaffinity Chromatography.
- 免疫原
- Synthetic Peptide corresponding to 20 Amino Acid peptide from near the amino terminus of human TP1.
- Top Product
- Discover our top product TEP1 Primary Antibody
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anti-Telomerase-Associated Protein 1 (TEP1) (AA 2368-2627) antibody
TEP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Immunohistochemistry on Paraffin Sections (5 μg/mL). Western Blot.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Phosphate Buffered Saline PBS containing 0.02 % Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Dilute only prior to immediate use. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
- 有效期
- 12 months
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- 抗原
- TEP1 (Telomerase-Associated Protein 1 (TEP1))
- 别名
- tep1,tlp1 (TEP1 产品)
- 别名
- TLP1 antibody, TP1 antibody, TROVE1 antibody, VAULT2 antibody, p240 antibody, Tp1 antibody, Tlp1 antibody, telomerase associated protein 1 antibody, TEP1 antibody, Tep1 antibody
- 背景
- Telomerase is an RNA-dependent DNA polymerase that uses an RNA component to add telomeric repeat sequences at the ends of chromosomes. Besides the RNA component which serves as the template that specifies the telomeric repeat, the telomerase complex contains a reverse transcriptase protein (TRT) and various accessory proteins including the telomerase-associated protein 1 (TEP1). Telomerase activity is low in most somatic cells, causing the gradual shortening of telomeres which can ultimately lead to telomere fusion and cell death. High levels of telomerase activity are widely seen in cancerous cells and while recent experiments have suggested that telomerase may be a viable target in cancer therapy, expression levels of TEP1 do not correlate with malignancy. At least two isoforms of TP1 are known to exist.
- UniProt
- Q99973
- 途径
- Inositol Metabolic Process, Synaptic Membrane, Regulation of Cell Size, Autophagy, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor
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