NMDA 1 Receptor 抗体 (pSer890)
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- 抗原 See all NMDA 1 Receptor (NMDA R1) 抗体
- NMDA 1 Receptor (NMDA R1) (NMDA Receptor 1 (NMDA R1))
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抗原表位
- pSer890
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NMDA 1 Receptor antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- The antibody detects endogenous levels of NMDAR1 only when phosphorylated at serine 890.
- 纯化方法
- Affinity chromatography using epitope-specific peptide
- 免疫原
- Peptide sequence around phosphorylation site of Serine 890(A-S-S(p)-F-K) derived from Human NMDAR1 (KLH-conjugated)
- Top Product
- Discover our top product NMDA R1 Primary Antibody
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anti-NMDA Receptor 1 (NMDA R1) (AA 35-53) antibody
NMDA R1 适用: 人, 大鼠, 小鼠 WB, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (AA 35-53) antibodyNMDA R1 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (Splice Variant C2') antibodyNMDA R1 适用: 人, 大鼠, 小鼠, Cow WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (Splice Variant C2) antibodyNMDA R1 适用: 人, 大鼠, 小鼠 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (AA 1-564), (N-Term) antibodyNMDA R1 适用: 大鼠, 小鼠 WB, IHC (fro), IP 宿主: 小鼠 Monoclonal R1JHL unconjugated
anti-NMDA Receptor 1 (NMDA R1) (pSer896) antibodyNMDA R1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (AA 895-899) antibodyNMDA R1 适用: 人, 大鼠, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (AA 894-898) antibodyNMDA R1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) (pSer897) antibodyNMDA R1 适用: 人, 大鼠, 小鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NMDA Receptor 1 (NMDA R1) antibodyNMDA R1 适用: 人, 大鼠, 小鼠 WB, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Immunohistochemistry on paraffin sections: 1:50~1:100. Immunofluorescence: 1:100~1:200.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
- 有效期
- 12 months
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- 抗原
- NMDA 1 Receptor (NMDA R1) (NMDA Receptor 1 (NMDA R1))
- 别名
- nmda receptor 1 (NMDA R1 产品)
- 别名
- CG2902 antibody, DMNMDAR1 antibody, DNMDAR-I antibody, DNmdar antibody, DmelNmdar1 antibody, Dmel\\CG2902 antibody, DrNR1 antibody, NMDA antibody, NMDA R1 antibody, NMDAR1 antibody, NMdar1 antibody, NR1 antibody, NRI antibody, Nmdar antibody, dNR1 antibody, dnmdar-I antibody, nmr antibody, NMDA receptor 1 antibody, Nmdar1 antibody
- 背景
- NMDA receptors are members of the ionotropic class of glutamate receptors, which also includes Kainate and AMPA receptors. NMDA receptors consist of NR1 subunits combined with one or more NR2 (A-D) or NR3 (A-B) subunits. The ligand-gated channel is permeable to cations including Ca2+, and at resting membrane potentials NMDA receptors are inactive due to a voltage-dependent blockade of the channel pore by Mg2+. NMDA receptor activation, which requires binding of glutamate and glycine, leads to an influx of Ca2+ into the postsynaptic region where it activates several signaling cascades, including pathways leading to the induction of long-term potentiation (LTP) and depression (LTD). NMDA receptors have a critical role in excitatory synaptic transmission and plasticity in the CNS. They govern a range of physiological conditions including neurological disorders caused by excitotoxic neuronal injury, psychiatric disorders and neuropathic pain syndromes.
- UniProt
- Q05586
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