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SIGLEC6 抗体 (C-Term)

SIGLEC6 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5534686
发货至: 中国
  • 抗原 See all SIGLEC6 抗体
    SIGLEC6 (Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6))
    抗原表位
    • 10
    • 8
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 381-412, C-Term
    适用
    • 51
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 47
    • 3
    • 1
    克隆类型
    • 49
    • 2
    多克隆
    标记
    • 26
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIGLEC6 antibody is un-conjugated
    应用范围
    • 39
    • 28
    • 15
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This SIGLEC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 381-412 amino acids from the C-terminal region of human SIGLEC6.
    亚型
    Ig Fraction
    Top Product
    Discover our top product SIGLEC6 Primary Antibody
  • 应用备注
    For IHC-P starting dilution is: 1:50~100

    For WB starting dilution is: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    SIGLEC6 (Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6))
    别名
    SIGLEC6 (SIGLEC6 产品)
    别名
    SIGLEC6 antibody, CD327 antibody, CD33L antibody, CD33L1 antibody, CD33L2 antibody, CDW327 antibody, OBBP1 antibody, sialic acid binding Ig like lectin 6 antibody, SIGLEC6 antibody
    背景
    SIGLEC6 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells by binding to alpha2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. SIGLEC6, which interacts with LEP, is expressed at high levels in placenta (cyto-and syncytiotrophoblastic cells) and at lower levels in spleen, peripheral blood leukocytes (predominantly B-cells) and small intestine. It contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in downmodulation of cellular responses. The phosphorylated ITIM motif binds to the SH2 domain of PTPN6/SHP-1. The gene for SIGLEC6 belongs to the immunoglobulin superfamily.
    分子量
    50 kDa
    基因ID
    946
    UniProt
    O43699
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