Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
纯化方法
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
免疫原
This FRAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-128 amino acids from the Central region of human FRAT1.
FRAT1
适用: 人
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 750
应用备注
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
限制
仅限研究用
状态
Liquid
浓度
2 mg/mL
缓冲液
Supplied in PBS with 0.09 % (W/V) sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
抗原
FRAT1
(Frequently Rearranged in Advanced T-Cell Lymphomas (FRAT1))
FRAT1 antibody, frat1 antibody, AW060382 antibody, gbp antibody, FRAT1, WNT signaling pathway regulator antibody, GSK-3 binding protein FRAT1 antibody, frequently rearranged in advanced T cell lymphomas antibody, frequently rearranged in advanced T-cell lymphomas antibody, frequently rearranged in advanced T-cell lymphomas 1 S homeolog antibody, FRAT1 antibody, frat1 antibody, Frat1 antibody, frat1.S antibody
背景
FRAT1 belongs to the GSK-3-binding protein family. It may function in tumor progression and in lymphomagenesis. It positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. It may play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis.