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MYLK 抗体 (N-Term)

Name: MYLK 抗体 (N-Term)
SKU: ABIN5533210
Availability: OutOfStock

MYLK 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Western blot analysis of lysate from mouse bladder tissue lysate, using MLCKlong Antibody (M1) at 1:1000. (MYLK 抗体 (N-Term))

Western blot analysis in SK-BR-3 cell line lysates (35ug/lane). (MYLK 抗体 (N-Term))

3 images

产品编号 ABIN5533210

发货至: 中国

Datasheet as PDF

抗原 See all MYLK 抗体

MYLK (Myosin Light Chain Kinase (MYLK))
抗原表位
15

8

8

7

5

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 908-938, N-Term
适用
77

40

35

2

2

1

1
人, 小鼠
宿主
85

4

3

1
兔
Compatible Secondaries
克隆类型
81

12
多克隆
标记
40

8

5

4

4

4

4

4

4

3

1

1

1

1

1

1

1

1

1

1

1

1

1
This MYLK antibody is un-conjugated
应用范围
37

36

25

13

13

9

5

4

4

3

2

2

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

纯化方法

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

免疫原

This MLCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 908-938 amino acids from the N-terminal region of human MLCK.

亚型

Ig Fraction

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anti-Myosin Light Chain Kinase (MYLK) (AA 1375-1524) antibody
MYLK 适用: 人, 小鼠 WB, ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 7F2B11 unconjugated

anti-Myosin Light Chain Kinase (MYLK) (AA 1684-1884) antibody
MYLK 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Myosin Light Chain Kinase (MYLK) (AA 1441-1709) antibody
MYLK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Myosin Light Chain Kinase (MYLK) (AA 1765-1914) antibody
MYLK 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Myosin Light Chain Kinase (MYLK) (AA 923-953), (N-Term) antibody
MYLK 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB03067 unconjugated

anti-Myosin Light Chain Kinase (MYLK) (AA 908-938) antibody
MYLK 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Myosin Light Chain Kinase (MYLK) (AA 1661-1877) antibody
MYLK 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Myosin Light Chain Kinase (MYLK) antibody
MYLK 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated

anti-Myosin Light Chain Kinase (MYLK) (AA 1-992) antibody
MYLK 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Myosin Light Chain Kinase (MYLK) (C-Term) antibody
MYLK 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

限制

仅限研究用
状态

Liquid

浓度

2 mg/mL

缓冲液

Supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
抗原

MYLK (Myosin Light Chain Kinase (MYLK))

别名

MLCK (MYLK 产品)

别名

AAT7 antibody, KRP antibody, MLCK antibody, MLCK1 antibody, MLCK108 antibody, MLCK210 antibody, MSTP083 antibody, MYLK1 antibody, smMLCK antibody, 9530072E15Rik antibody, A930019C19Rik antibody, AW489456 antibody, Mlck antibody, SMMLCK antibody, mlck antibody, fj60a06 antibody, mlck1a antibody, mylk antibody, wu:fj60a06 antibody, zmlck1 antibody, myosin light chain kinase antibody, myosin, light polypeptide kinase antibody, myosin, light chain kinase a antibody, MYLK antibody, Mylk antibody, mylka antibody

背景

MLCK, a member of the Ser/Thr protein kinase family, is a calcium/calmodulin-dependent enzyme responsible for smooth muscle contraction via phosphorylation of a specific serine in the N-terminus of myosin light chains (MLC), an event that facilitates myosin interaction with actin filaments. It is a central determinant in the development of vascular permeability and tissue edema formation. In the nervous system it has been shown to control the growth initiation of astrocytic processes in culture and to participate in transmitter release at synapses formed between cultured sympathetic ganglion cells. MLCK acts as a critical participant in signaling sequences that result in fibroblast apoptosis. Smooth muscle and non-muscle isozymes are expressed in a wide variety of adult and fetal tissues and in cultured endothelium with qualitative expression appearing to be neither tissue- nor development-specific. Non-muscle isoform 2 is the dominant splice variant expressed in various tissues. The Telokin isoform, which binds calmodulin, has been found in a wide variety of adult and fetal tissues. MLCK is probably down-regulated by phosphorylation. The protein contains 1 fibronectin type III domain and 9 immunoglobulin-like C2-type domains.

分子量

211 kDa

基因ID

4638

UniProt

Q15746