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TEAD2 抗体 (AA 267-295)

TEAD2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5532239
发货至: 中国
  • 抗原 See all TEAD2 抗体
    TEAD2 (TEA Domain Family Member 2 (TEAD2))
    抗原表位
    • 15
    • 9
    • 7
    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 267-295
    适用
    • 37
    • 29
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 43
    • 8
    • 1
    克隆类型
    • 46
    • 6
    多克隆
    标记
    • 21
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TEAD2 antibody is un-conjugated
    应用范围
    • 24
    • 23
    • 13
    • 13
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This TEAD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 267-295 amino acids from the Central region of human TEAD2.
    亚型
    Ig Fraction
    Top Product
    Discover our top product TEAD2 Primary Antibody
  • 应用备注
    For WB starting dilution is: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    TEAD2 (TEA Domain Family Member 2 (TEAD2))
    别名
    TEAD2 (TEAD2 产品)
    别名
    TEAD2 antibody, ETF antibody, TEAD-2 antibody, TEF-4 antibody, TEF4 antibody, Etdf antibody, TEA domain transcription factor 2 antibody, TEA domain family member 2 antibody, TEAD2 antibody, Tead2 antibody
    背景
    Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.
    分子量
    49 kDa
    基因ID
    8463
    UniProt
    Q15562
    途径
    Regulation of Lipid Metabolism by PPARalpha, Tube Formation
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