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- 抗原 See all PRDM6 抗体
- PRDM6 (PR Domain Containing 6 (PRDM6))
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抗原表位
- AA 44-72, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRDM6 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This PRDM6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-72 amino acids from the N-terminal region of human PRDM6.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product PRDM6 Primary Antibody
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anti-PR Domain Containing 6 (PRDM6) (AA 448-477) antibody
PRDM6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-PR Domain Containing 6 (PRDM6) (AA 376-595) antibodyPRDM6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-PR Domain Containing 6 (PRDM6) (N-Term) antibodyPRDM6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- For WB starting dilution is: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.35 mg/mL
- 缓冲液
- Supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- PRDM6 (PR Domain Containing 6 (PRDM6))
- 别名
- PRDM6 (PRDM6 产品)
- 别名
- Gm92 antibody, PRISM antibody, RGD1559594 antibody, PRDM6 antibody, PR/SET domain 6 antibody, PR domain containing 6 antibody, putative histone-lysine N-methyltransferase PRDM6 antibody, PRDM6 antibody, Prdm6 antibody, LOC100354345 antibody, prdm6 antibody
- 背景
- Putative histone methyltransferase that acts as a transcriptional repressor of smooth muscle gene expression. Promotes the transition from differentiated to proliferative smooth muscle by suppressing differentiation and maintaining the proliferative potential of vascular smooth muscle cells. Also plays a role in endothelial cells by inhibiting endothelial cell proliferation, survival and differentiation. It is unclear whether it has histone methyltransferase activity in vivo. According to some authors, it does not act as a histone methyltransferase by itself and represses transcription by recruiting EHMT2/G9a. According to others, it possesses histone methyltransferase activity when associated with other proteins and specifically methylates 'Lys-20' of histone H4 in vitro. 'Lys-20' methylation represents a specific tag for epigenetic transcriptional repression (By similarity).
- 分子量
- 64 kDa
- 基因ID
- 93166
- UniProt
- Q9NQX0
- 途径
- Regulation of Muscle Cell Differentiation
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