Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
纯化方法
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
免疫原
This PRMT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-53 amino acids from the N-terminal region of human PRMT2.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C,-20 °C
储存方法
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
PRMT2 antibody, DKFZp459N1919 antibody, HRMT1L1 antibody, Hrmt1l1 antibody, AI504737 antibody, protein arginine methyltransferase 2 antibody, protein arginine methyltransferase 2 L homeolog antibody, protein arginine N-methyltransferase 2 antibody, PRMT2 antibody, Prmt2 antibody, prmt2.L antibody
背景
Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.