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CD300E 抗体

This anti-CD300E antibody is a 小鼠 单克隆 antibody detecting CD300E in WB, FACS, IP 和 Func. Suitable for 人.
产品编号 ABIN5526907
发货至: 中国

Quick Overview for CD300E 抗体 (ABIN5526907)

抗原

See all CD300E 抗体
CD300E (CD300e Molecule (CD300E))

适用

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宿主

  • 17
  • 10
小鼠

克隆类型

  • 18
  • 9
单克隆

标记

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This CD300E antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)

克隆位点

UP-H2
  • 原理

    Anti-Hu CD300e Purified Low Endotoxin

    特异性

    The mouse monoclonal antibody UP-H2 recognizes an extracellular epitope on CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells.

    交叉反应 (详细)

    Human

    纯化方法

    Purified by protein-A affinity chromatography.

    纯度

    > 95 % (by SDS-PAGE)

    内毒素水平

    Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.

    免疫原

    CD300e-HA-transfected cells

    亚型

    IgG1 kappa
  • 应用备注

    Functional application: Stimulation.
    Flow cytometry: Recommended dilution: 1-4 μg/mL

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • 抗原

    CD300E (CD300e Molecule (CD300E))

    别名

    CD300e

    背景

    CD300e molecule,CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.,CLM2, CMRF35-A5, LMIR6, IREM-2, PlgR2

    基因ID

    342510

    UniProt

    Q496F6
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