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- 抗原 See all PVRL1 抗体
- PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PVRL1 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The mouse monoclonal antibody R1.302 recognizes an extracellular epitope on CD111 (also known as Nectin 1), a 75 kDa type I transmembrane glycoprotein broadly expressed on endothelial cells, epithelial cells, neuronal cells, megakaryocytes, and CD34-positive stem cells.
- 交叉反应 （详细）
- Human
- 纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 免疫原
- NIH/3T3 cells transfected with human CD111
- 克隆位点
- R1-302
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product PVRL1 Primary Antibody
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anti-Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) (AA 177-190), (Extracellular), (N-Term) antibody
PVRL1 适用: 人, 小鼠, 大鼠 WB, FACS, IHC, IF, LCI, ICC 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) (AA 1-352) antibodyPVRL1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) (AA 1-352) antibodyPVRL1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) (AA 31-130) antibodyPVRL1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro), DB 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) (AA 33-142) antibodyPVRL1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) (AA 137-186) antibodyPVRL1 适用: 人, Cow, 犬, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) antibodyPVRL1 适用: 人 WB, FACS, IHC, IP, ICC 宿主: 小鼠 Monoclonal R1-302 unconjugated
anti-Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) (AA 70-350) antibodyPVRL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- 说明
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The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
- 限制
- 仅限研究用
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- 缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- 抗原
- PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))
- 别名
- CD111 (PVRL1 产品)
- 背景
- Nectin cell adhesion molecule 1,CD111, also known as nectin-1, is a calcium-independent cell-cell adhesion transmembrane glycoprotein involved in organization of adherens junctions and tight junctions in epithelial and endothelial cells. It also serves as a target molecule for entry of herpes simplex virus (HSV-1, HSV-2) and pseudorabies virus (PRV) into epithelial and neuronal cells. CD111 is connected with actin cytoskeleton through afadin. Mutations in the gene for CD111 cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.,NECTIN1, ED4, HIgR, HV1S, HVEC, OFC7, PRR1, PVRR, CD111, PVRL1, PVRR1, SK-12, CLPED1
- 基因ID
- 5818
- UniProt
- Q15223
- 途径
- Cell-Cell Junction Organization
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