PVRL1 抗体 (PE)
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- 抗原 See all PVRL1 抗体
- PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PVRL1 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The mouse monoclonal antibody R1.302 recognizes an extracellular epitope on CD111 (also known as Nectin 1), a 75 kDa type I transmembrane glycoprotein broadly expressed on endothelial cells, epithelial cells, neuronal cells, megakaryocytes, and CD34-positive stem cells.
- 交叉反应 (详细)
- Human
- 纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 免疫原
- NIH/3T3 cells transfected with human CD111
- 克隆位点
- R1-302
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product PVRL1 Primary Antibody
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- 应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- 说明
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The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
- 限制
- 仅限研究用
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- 缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- 抗原
- PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))
- 别名
- CD111 (PVRL1 产品)
- 别名
- CD111 antibody, CLPED1 antibody, ED4 antibody, HIgR antibody, HVEC antibody, OFC7 antibody, PRR antibody, PRR1 antibody, PVRR antibody, PVRR1 antibody, SK-12 antibody, nectin-1 antibody, prr1 antibody, PVRL1 antibody, pvrl1 antibody, AI835281 antibody, AW549174 antibody, Cd111 antibody, HveC antibody, cd111 antibody, cd112 antibody, clped1 antibody, ed4 antibody, higr antibody, hveb antibody, hvec antibody, nectin-2 antibody, ofc7 antibody, prr antibody, prr2 antibody, pvrl2 antibody, pvrl2.L antibody, pvrr antibody, pvrr1 antibody, pvrr2 antibody, sk-12 antibody, nectin cell adhesion molecule 1 antibody, nectin-1 antibody, Poliovirus receptor-related protein 1 antibody, poliovirus receptor-related 1 (herpesvirus entry mediator C) antibody, nectin cell adhesion molecule 2 L homeolog antibody, NECTIN1 antibody, LOC100145553 antibody, pvrl1 antibody, nectin1 antibody, Nectin1 antibody, PVRL1 antibody, nectin2.L antibody
- 背景
- Nectin cell adhesion molecule 1,CD111, also known as nectin-1, is a calcium-independent cell-cell adhesion transmembrane glycoprotein involved in organization of adherens junctions and tight junctions in epithelial and endothelial cells. It also serves as a target molecule for entry of herpes simplex virus (HSV-1, HSV-2) and pseudorabies virus (PRV) into epithelial and neuronal cells. CD111 is connected with actin cytoskeleton through afadin. Mutations in the gene for CD111 cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.,NECTIN1, ED4, HIgR, HV1S, HVEC, OFC7, PRR1, PVRR, CD111, PVRL1, PVRR1, SK-12, CLPED1
- 基因ID
- 5818
- UniProt
- Q15223
- 途径
- Cell-Cell Junction Organization
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