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TIMP1 抗体 (AA 24-207)

Name: TIMP1 抗体 (AA 24-207)
SKU: ABIN5519064
Availability: OutOfStock

TIMP1 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

Western blot analysis of TIMP1 using anti-TIMP1 antibody . (TIMP1 抗体 (AA 24-207))

1 image

(14 references)

产品编号 ABIN5519064

发货至: 中国

Datasheet as PDF

抗原 See all TIMP1 抗体

TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))
抗原表位
17

15

15

12

9

6

5

4

3

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
AA 24-207
适用
143

73

71

24

7

6

5

5

2

2

1

1

1
人, 大鼠, 小鼠
宿主
129

54

6

1

1
兔
Compatible Secondaries
克隆类型
132

58
多克隆
标记
83

22

15

7

4

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

3

2

2

2
This TIMP1 antibody is un-conjugated
应用范围
132

62

52

39

26

23

22

20

16

15

11

9

7

6

4

4

4

4

3

2

1

1

1

1

1
Western Blotting (WB), ELISA

原理

Rabbit IgG polyclonal antibody for TIMP1 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for TIMP1 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
Gene Name: TIMP metallopeptidase inhibitor 1
Protein Name: Metalloproteinase inhibitor 1

纯化方法

Immunogen affinity purified.

免疫原

E. coli-derived huamn TIMP1 recombinant protein (Position: C24-A207).

亚型

IgG

Top Product

Discover our top product TIMP1 Primary Antibody
anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 103-207) antibody
TIMP1 适用: 人, 大鼠, 小鼠, 兔 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 157-188), (C-Term) antibody
TIMP1 适用: 人 WB, IHC (p), FACS, IF 宿主: 兔 Polyclonal RB14602 unconjugated

anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 41-70), (N-Term) antibody
TIMP1 适用: 人 WB, IHC (p), FACS, IF 宿主: 兔 Polyclonal RB15494 unconjugated

anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 25-207) antibody
TIMP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 24-207) antibody
TIMP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) antibody
TIMP1 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 8B4E9 unconjugated

anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 1-169) antibody
TIMP1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 4D12 unconjugated

anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 24-207) antibody
TIMP1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 131-207) antibody
TIMP1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) (AA 24-217) antibody
TIMP1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Liu, Liu, Tan, Tang, Long, Li, Liang, Chu, Yang: "Gaseous signalling molecule SO2 via Hippo‑MST pathway to improve myocardial fibrosis of diabetic rats." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 8953-8963, (2018) (PubMed).

"Retraction: Naringin Alleviates Diabetic Kidney Disease through Inhibiting Oxidative Stress and Inflammatory Reaction." in: PLoS ONE, Vol. 13, Issue 2, pp. e0192465, (2018) (PubMed).

Wang, Jiang, Xue: "Recombinant human endostatin reduces hypertrophic scar formation in rabbit ear model through down-regulation of VEGF and TIMP-1." in: African health sciences, Vol. 16, Issue 2, pp. 542-53, (2017) (PubMed).

Yang, Luo, Zhu, Zhou, Wang, Xue, Zhang, Cai, Chen, Ma, Chen, Wang, Luo, Liu, Zhao: "Chlorogenic Acid Inhibits Liver Fibrosis by Blocking the miR-21-Regulated TGF-β1/Smad7 Signaling Pathway in Vitro and in Vivo." in: Frontiers in pharmacology, Vol. 8, pp. 929, (2017) (PubMed).

Chen, Zhang, Ma, Huang, Shao, Wu, Wang: "Naringin Alleviates Diabetic Kidney Disease through Inhibiting Oxidative Stress and Inflammatory Reaction." in: PLoS ONE, Vol. 10, Issue 11, pp. e0143868, (2016) (PubMed).

Fan, Jiang, Li, Fang, Xu, Zheng: "MMP-1/2 and TIMP-1/2 expression levels, and the levels of collagenous and elastic fibers correlate with disease progression in a hamster model of tongue cancer." in: Oncology letters, Vol. 11, Issue 1, pp. 63-68, (2016) (PubMed).

Di, Nie, Chen: "Matrix metalloproteinase-9 and vascular endothelial growth factor expression change in experimental retinal neovascularization." in: International journal of ophthalmology, Vol. 9, Issue 6, pp. 804-8, (2016) (PubMed).

Deng, Ling, Liu, Zhao, Lv: "Decreased expression of matrix metalloproteinase-1 in the maternal umbilical serum, trophoblasts and decidua leads to preeclampsia." in: Experimental and therapeutic medicine, Vol. 9, Issue 3, pp. 992-998, (2015) (PubMed).

Yin, Li, Gao, Li, Li: "Andrographolide plays an important role in bleomycin-induced pulmonary fibrosis treatment." in: International journal of clinical and experimental medicine, Vol. 8, Issue 8, pp. 12374-81, (2015) (PubMed).

Xu, Dai, Liu, Liu, Song, Li, Chen, Lin: "Sanmiao formula inhibits chondrocyte apoptosis and cartilage matrix degradation in a rat model of osteoarthritis." in: Experimental and therapeutic medicine, Vol. 8, Issue 4, pp. 1065-1074, (2014) (PubMed).

Zhong, Wang, Jian: "Expression of matrix metalloproteinases-8 and -9 and their tissue inhibitor in the condyles of diabetic rats with mandibular advancement." in: Experimental and therapeutic medicine, Vol. 8, Issue 5, pp. 1357-1364, (2014) (PubMed).

Ma, Ma, Ma, Sun, Yu, Wang, Li, Ding: "The Effects of Uygur Herb Hyssopus officinalis L. on the Process of Airway Remodeling in Asthmatic Mice." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 710870, (2014) (PubMed).

Li, Liu, Zhang, Zhu, He, Xiao: "Effects of augmentation of liver regeneration recombinant plasmid on rat hepatic fibrosis." in: World journal of gastroenterology, Vol. 11, Issue 16, pp. 2438-43, (2005) (PubMed).

Yang, Xie, Geng, Luo, Han, Cheng: "Effect of Danshao Huaxian capsule on expression of matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 in fibrotic liver of rats." in: World journal of gastroenterology, Vol. 11, Issue 32, pp. 4953-6, (2005) (PubMed).
抗原

TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

别名

TIMP1 (TIMP1 产品)

别名

TIMP-1 antibody, TIMP1 antibody, DKFZp468A0912 antibody, CLGI antibody, EPA antibody, EPO antibody, HCI antibody, TIMP antibody, Timp antibody, Clgi antibody, TIMP metallopeptidase inhibitor 1 antibody, tissue inhibitor of metalloproteinase 1 antibody, TIMP1 antibody, Timp1 antibody

背景

TIMP metallopeptidase inhibitor 1, also known as TIMP1, a tissue inhibitor of metalloproteinases, is a glycoprotein that is expressed from the several tissues of organisms. This protein is a member of the TIMP family. The glycoprotein is a natural inhibitor of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. TIMP was found to be located about 22 cM proximal to OTC (300461).

Synonyms: Metalloproteinase inhibitor 1, Erythroid-potentiating activity, EPA, Fibroblast collagenase inhibitor, Collagenase inhibitor, Tissue inhibitor of metalloproteinases 1, TIMP-1, TIMP1, CLGI, TIMP

基因ID

7076

UniProt

P01033