C19ORF80 抗体 (AA 22-198)
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- 抗原 See all C19ORF80 抗体
- C19ORF80 (Chromosome 19 Open Reading Frame 80 (C19ORF80))
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抗原表位
- AA 22-198
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This C19ORF80 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Angiopoietin-like protein 8 (ANGPTL8) detection. Tested with WB in Human.
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Angiopoietin-like protein 8 (ANGPTL8) detection. Tested with WB in Human.
Gene Name: angiopoietin like 8
Protein Name: Angiopoietin-like protein 8 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human C19orf80 recombinant protein (Position: A22-A198). Human C19orf80 shares 74% amino acid (aa) sequence identity with mouse C19orf80.
- 亚型
- IgG
- Top Product
- Discover our top product C19ORF80 Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- C19ORF80 (Chromosome 19 Open Reading Frame 80 (C19ORF80))
- 别名
- ANGPTL8 (C19ORF80 产品)
- 别名
- ANGPTL8 antibody, PRO1185 antibody, PVPA599 antibody, RIFL antibody, TD26 antibody, angiopoietin like 8 antibody, ANGPTL8 antibody
- 背景
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ANGPTL8 (also known as lipasin, originally Betatrophin) is a protein that in humans is encoded by the C19orf80 gene. The gene for betatrophin lies on mouse chromosome 9 (gene symbol: Gm6484) and on human chromosome 19 (gene symbol: C19orf80). The encoded 22 kDa protein contains an N-terminal secretion signal and two coiled-coil domains and is a member of the angiopoietin-like (ANGPTL) protein family. However, in contrast to other ANGPTL proteins, betatrophin lacks the C-terminal fibrinogen-like domain, and therefore it is an atypical member of the ANGPTL family. It shares with Angptl4 and Angptl3 the ability to inhibit the enzyme Lipoprotein lipase (LPL), and its hepatic overexpression causes elevation of circulating Triglyceride levels in mice. In mice betatrophin is secreted by the liver. It was hoped that betatrophin or its homolog in humans may provide an effective treatment for type 2 diabetes and perhaps even type I diabetes.
Synonyms: Angiopoietin-like protein 8, Betatrophin, Lipasin, Refeeding-induced fat and liver protein, ANGPTL8, C19orf80, RIFL, UNQ599/PRO1185 - 基因ID
- 55908
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