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CD147 抗体 (AA 138-323)

Name: CD147 抗体 (AA 138-323)
SKU: ABIN5518743
Availability: OutOfStock

BSG 适用: 人, 小鼠, 大鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated

IHC analysis of CD147/Emmprin using anti-CD147/Emmprin antibody . (CD147 抗体 (AA 138-323))

IHC

Western blot analysis of CD147/Emmprin using anti-CD147/Emmprin antibody . (CD147 抗体 (AA 138-323))

IHC

Flow Cytometry analysis of A549 cells using anti-CD147/Emmprin antibody . (CD147 抗体 (AA 138-323))

FACS

Flow Cytometry analysis of Hela cells using anti-CD147/Emmprin antibody . (CD147 抗体 (AA 138-323))

FACS

IHC

9 images

(3 references)

产品编号 ABIN5518743

发货至: 中国

Datasheet as PDF

抗原 See all CD147 (BSG) 抗体

CD147 (BSG) (Basigin (Ok Blood Group) (BSG))
抗原表位
16

9

7

7

6

6

5

3

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 138-323
适用
146

39

38

17

4

4

4

2

2

2

1

1

1

1

1

1
人, 小鼠, 大鼠
宿主
81

74

7
兔
Compatible Secondaries
克隆类型
87

74
多克隆
标记
75

13

12

11

7

4

4

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD147 antibody is un-conjugated
应用范围
87

87

33

32

26

24

15

14

13

10

9

9

6

3

2

2

1

1

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

原理

Rabbit IgG polyclonal antibody for Basigin(BSG) detection. Tested with WB, IHC-P, FCM in Human,Mouse,Rat.

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Basigin(BSG) detection. Tested with WB, IHC-P, FCM in Human,Mouse,Rat.
Gene Name: basigin (Ok blood group)
Protein Name: Basigin

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human CD147/Emmprin recombinant protein (Position: E138-A323). Human CD147/Emmprin shares 51.1% and 51.9% amino acid (aa) sequence identity with mouse and rat CD147/Emmprin, respectively.

亚型

IgG

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anti-Basigin (Ok Blood Group) (BSG) (AA 138-323) antibody
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anti-Basigin (Ok Blood Group) (BSG) (AA 1-269) antibody
BSG 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Basigin (Ok Blood Group) (BSG) antibody
BSG 适用: 人, Pig FACS, IHC (p) 宿主: 小鼠 Monoclonal MEM-M6-2 unconjugated

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Flow Cytometry: Concentration: 1-3 μg/1x106 cells, Tested Species: Human
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Zhang, Yang, Liu, Liu, Teng, Zhang, Yin, Liu et al.: "iTRAQ-coupled 2D LC/MS-MS analysis of CXCR7-transfected papillary thyroid carcinoma cells: A new insight into CXCR7 regulation of papillary thyroid carcinoma progression and identification of ..." in: Oncology letters, Vol. 14, Issue 3, pp. 3734-3740, (2017) (PubMed).

Xiao, Zhao, Shen, Liang, Chen: "Overexpression of CD147 is associated with poor prognosis, tumor cell migration and ERK signaling pathway activation in hepatocellular carcinoma." in: Experimental and therapeutic medicine, Vol. 14, Issue 3, pp. 2637-2642, (2017) (PubMed).

Lu, Lv, Kim, Ha, Kim: "Expression and clinical significance of extracellular matrix metalloproteinase inducer, EMMPRIN/CD147, in human osteosarcoma." in: Oncology letters, Vol. 5, Issue 1, pp. 201-207, (2012) (PubMed).
抗原

CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

别名

BSG (BSG 产品)

别名

EMMPRIN antibody, RPE7 antibody, 5F7 antibody, CD147 antibody, M6 antibody, OK antibody, TCSF antibody, AI115436 antibody, AI325119 antibody, HT-7 antibody, 5A11 antibody, CE9 antibody, HT7 antibody, Ox47R antibody, basignin antibody, wu:fb26a05 antibody, wu:fo98e12 antibody, bsg antibody, prso03 antibody, basigin (Ok blood group) antibody, basigin antibody, basigin (Ok blood group) S homeolog antibody, BSG antibody, Bsg antibody, bsg antibody, bsg.S antibody

背景

Emmprin, extracellular matrix metalloproteinase inducer, also known as Emmprin (BSG) or cluster of differentiation 147 (CD147) is a protein that in humans is encoded by the Emmprin gene. The human BSG gene is mapped to 19p13.3. This protein is a determinant for the Ok blood group system. BSG has been shown to be an essential receptor on red blood cells for the malaria parasite. It is a member of the immunoglobulin superfamily, with a structure related to the putative primordial form of the family. As members of the immunoglobulin superfamily, it plays fundamental roles in intercellular recognition involved in various immunologic phenomena, differentiation, and development. BSG is thought also to play a role in intercellular recognition. It also regulates several distinct functions, such as spermatogenesis, expression of the monocarboxylate transporter and the responsiveness of lymphocytes. BSG is a type I integral membrane receptor that has many ligands, including the cyclophilin (CyP) proteins Cyp-A and CyP-B and certain integrins. It is expressed by many cell types, including epithelial cells, endothelial cells and leukocytes.

Synonyms: 5A11 antigen | 5F7 | BASI | Basigin | basigin (Ok blood group) | Basigin(Ok blood group) | BSG | CD147 antigen | Collagenase stimulatory factor | Emmprin | HT7 antigen | Leukocyte activation antigen M6 | neurothelin | OK blood group antigen | OX-47 antigen | P35613 | TCSF

基因ID

682

UniProt

P35613

途径

S100 Proteins