ABCG8 抗体 (Middle Region)
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- 抗原 See all ABCG8 抗体
- ABCG8 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8))
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抗原表位
- AA 328-371, Middle Region
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ABCG8 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family G member 8(ABCG8) detection. Tested with WB in Human,Mouse,Rat.
- 序列
- DRRSREQELA TREKAQSLAA LFLEKVRDLD DFLWKAETKD LDED
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for ATP-binding cassette sub-family G member 8(ABCG8) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: ATP binding cassette subfamily G member 8
Protein Name: ATP-binding cassette sub-family G member 8 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human ABCG8 (328-371aa DRRSREQELATREKAQSLAALFLEKVRDLDDFLWKAETKDLDED), different from the related mouse and rat sequences by twelve amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product ABCG8 Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- ABCG8 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 8 (ABCG8))
- 别名
- ABCG8 (ABCG8 产品)
- 别名
- DDBDRAFT_0167690 antibody, DDBDRAFT_0191232 antibody, DDB_0167690 antibody, DDB_0191232 antibody, zgc:172358 antibody, GBD4 antibody, STSL antibody, 1300003C16Rik antibody, AI114946 antibody, sterolin-2 antibody, ATP binding cassette subfamily G member 8 antibody, ATP-binding cassette sub-family G member 8 antibody, ABC transporter G family protein antibody, ATP-binding cassette, sub-family G (WHITE), member 8 antibody, ABCG8 antibody, PTRG_02054 antibody, abcG8 antibody, abcg8 antibody, Abcg8 antibody
- 背景
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ATP-binding cassette sub-family G member 8 is a protein that in humans is encoded by the ABCG8 gene. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia.
Synonyms: ABCG8 | GBD4 | Sterolin 2 | Sterolin-2 | TSL | Q9H221 - 基因ID
- 64241
- UniProt
- Q9H221
- 途径
- Lipid Metabolism
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