WDR40C antibody, A130007F10Rik antibody, Wdr40c antibody, DDB1 and CUL4 associated factor 12 like 2 antibody, DDB1 and CUL4 associated factor 12-like 2 antibody, DCAF12L2 antibody, Dcaf12l2 antibody
背景
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by Gly-His and Trp-Asp (GH-WD), which may facilitate formation of heterotrimeric or multi-protein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene appears to represent an intronless retrocopy of a related multi-exon gene located on chromosome 9. However, the CDS of this intronless gene remains intact, it is conserved in other mammalian species, it is known to be transcribed, and it is therefore thought to encode a functional protein.