DDBDRAFT_0204850 antibody, DDBDRAFT_0231505 antibody, DDB_0204850 antibody, DDB_0231505 antibody, DDBDRAFT_0187542 antibody, DDBDRAFT_0220113 antibody, DDB_0187542 antibody, DDB_0220113 antibody, HU-K4 antibody, HUK4 antibody, Sam-9 antibody, phospholipase D3 antibody, phospholipase D family member 3 antibody, phospholipase D family, member 3 antibody, CpipJ_CPIJ017227 antibody, pldZ antibody, pldY antibody, DICPUDRAFT_30308 antibody, PLD3 antibody, Pld3 antibody
背景
This gene encodes a member of the phospholipase D (PLD) family of enzymes that catalyze the hydrolysis of membrane phospholipids. The encoded protein is a single-pass type II membrane protein and contains two PLD phosphodiesterase domains. This protein influences processing of amyloid-beta precursor protein. Mutations in this gene are associated with Alzheimer disease risk. Alternatively spliced transcript variants encoding the same protein have been found for this gene.