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SETD7 抗体 (N-Term)
SETD7
适用: 人, 小鼠, 大鼠, 犬, 马, Pig, 兔, Cow, 斑马鱼, 豚鼠
WB
宿主: 兔
Polyclonal
unconjugated
SETD7抗体详情
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抗原
See all SETD7 抗体
SETD7
(SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
抗原表位
All epitopes for SETD7 抗体
N-Term
适用
All reactivities for SETD7 抗体
人, 小鼠, 大鼠, 犬, 马, Pig, 兔, Cow, 斑马鱼, 豚鼠
宿主
All hosts for SETD7 抗体
兔
克隆类型
All clonalities for SETD7 抗体
多克隆
标记
All conjugates for SETD7 抗体
This SETD7 antibody is un-conjugated
应用范围
All applications for SETD7 抗体
Western Blotting (WB)
序列
MDSDDEMVEE AVEGHLDDDG LPHGFCTVTY SSTDRFEGNF VHGEKNGRGK
预测反应
Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
产品特性
This is a rabbit polyclonal antibody against SETD7. It was validated on Western Blot.
纯化方法
Affinity purified
免疫原
The immunogen is a synthetic peptide directed towards the N-terminal region of Human SETD7
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Discover our top product SETD7 Primary Antibody
Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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状态
Liquid
缓冲液
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
SETD7目标详情
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抗原
SETD7
(SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
别名
SETD7 (SETD7 产品 )
别名
KMT7 antibody, SET7 antibody, SET7/9 antibody, SET9 antibody, set7 antibody, zgc:101860 antibody, zgc:92330 antibody, 1600028F23Rik antibody, H3K4MT antibody, Set7 antibody, Set7/9 antibody, mKIAA1717 antibody, SET domain containing lysine methyltransferase 7 antibody, SET domain containing (lysine methyltransferase) 7 antibody, SETD7 antibody, setd7 antibody, Setd7 antibody
背景
SETD7 is a histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. It plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation. Alias Symbols: SETD7, KIAA1717, KMT7, SET7, SET9, Protein Interaction Partner: KLF4, HIST3H3, SOX2, PRKAR1A, A1BG, TP53, NR2F2, STEAP3, SERTAD1, DPY30, MED1, MYOD1, E2F1, HIST1H3A, SMARCA4, H3F3A, STAT3, RELA, AR, UBC, DNMT1, PPP1R12A, SIRT1, TBP, TAF10, TAF7, TAF6, HIST1H4A, ESR1, HIST2H3C, HCFC1, L3MBTL1, Protein Size: 366
基因ID
80854
NCBI登录号
NP_085151
UniProt
Q8WTS6
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