PELI2 抗体 (N-Term)
PELI2
适用: 人, 小鼠, 大鼠, Pig, 兔, Cow, 斑马鱼, 犬, 豚鼠, 马
WB
宿主: 兔
Polyclonal
unconjugated
1 image
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- 抗原 See all PELI2 抗体
- PELI2 (Pellino Homolog 2 (Drosophila) (PELI2))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, Pig, 兔, Cow, 斑马鱼, 犬, 豚鼠, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PELI2 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- STISRFACRI VCDRNEPYTA RIFAAGFDSS KNIFLGEKAA KWKNPDGHMD
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- 产品特性
- This is a rabbit polyclonal antibody against PELI2. It was validated on Western Blot.
- 纯化方法
- Affinity purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human PELI2
- Top Product
- Discover our top product PELI2 Primary Antibody
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anti-Pellino Homolog 2 (Drosophila) (PELI2) (AA 1-420) antibody
PELI2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Pellino Homolog 2 (Drosophila) (PELI2) (AA 22-51), (N-Term) antibodyPELI2 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- PELI2 (Pellino Homolog 2 (Drosophila) (PELI2))
- 别名
- PELI2 (PELI2 产品)
- 背景
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PELI2 is a E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. It is involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. It mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination. It may be important for LPS- and IL1B-induced MAP3K7- dependent, but not MAP3K3-dependent, NF-kappa-B activation. And it can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1.
Protein Interaction Partner: SRPK1, FRYL, CREB3L3, THAP7, ERO1L, DEAF1, LAMC3, PICALM, LTBP3, IRAK1, HNRNPK, FN1, UBC, UBQLN4, IRAK4, TRAF6, NR2C2, BCL10, MYD88, IRAK2,
Protein Size: 420 - 基因ID
- 57161
- NCBI登录号
- NP_067078
- UniProt
- Q9HAT8
- 途径
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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