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FBXL15 抗体 (N-Term)

FBXL15 适用: 人, Cow, 犬, 山羊, 马, 小鼠, 兔, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5517039
发货至: 中国
  • 抗原 See all FBXL15 抗体
    FBXL15 (F-Box and Leucine-Rich Repeat Protein 15 (FBXL15))
    抗原表位
    • 7
    • 7
    • 6
    N-Term
    适用
    人, Cow, 犬, 山羊, 马, 小鼠, 兔, 大鼠
    宿主
    • 14
    克隆类型
    • 14
    多克隆
    标记
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    This FBXL15 antibody is un-conjugated
    应用范围
    • 14
    • 13
    • 12
    • 1
    Western Blotting (WB)
    序列
    PPMEPSGGEQ EPGAVRFLDL PWEDVLLPHV LNRVPLRQLL RLQRVSRAFR
    预测反应
    Cow: 93%, Dog: 100%, Goat: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%
    产品特性
    This is a rabbit polyclonal antibody against FBXL15. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human FBXL15
    Top Product
    Discover our top product FBXL15 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    FBXL15 (F-Box and Leucine-Rich Repeat Protein 15 (FBXL15))
    别名
    FBXL15 (FBXL15 产品)
    别名
    0710008C12Rik antibody, Fbxo37 antibody, RGD1306444 antibody, fbl15 antibody, fbxo37 antibody, FBXO37 antibody, Fbl15 antibody, JET antibody, PSD antibody, F4I10.140 antibody, F4I10_140 antibody, SLOW MOTION antibody, fbxl15 antibody, zgc:85882 antibody, F-box and leucine-rich repeat protein 15 antibody, F-box and leucine-rich repeat protein 15 L homeolog antibody, F-box and leucine rich repeat protein 15 antibody, F-box family protein antibody, F-box only protein 37 antibody, Fbxl15 antibody, fbxl15.L antibody, FBXL15 antibody, fbxl15 antibody, SLOMO antibody, fbx37 antibody
    背景
    FBXL15 is a substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. It is required for dorsal/ventral pattern formation and bone mass maintenance and also mediates ubiquitination of SMURF2 and WWP2.

    Alias Symbols: FBXO37, Fbl15, JET, PSD

    Protein Interaction Partner: HNRNPD, SKP1, ITCH, SMURF2, HECW2, SMURF1, NEDD4L, HECW1, WWP2, WWP1, RBX1, CUL1, NEDD4, HSP90AA1, COPS6, UBC,

    Protein Size: 300
    基因ID
    79176
    NCBI登录号
    NM_024326, NP_077302
    UniProt
    Q9H469
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