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APEX2 抗体 (C-Term)

APEX2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5515372
发货至: 中国
  • 抗原 See all APEX2 抗体
    APEX2 (APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2))
    抗原表位
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 20
    • 2
    • 1
    宿主
    • 20
    • 2
    克隆类型
    • 22
    多克隆
    标记
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    This APEX2 antibody is un-conjugated
    应用范围
    • 20
    • 15
    • 15
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    LMTPKTPEEK AVAKVVKGQA KTSEAKDEKE LRTSFWKSVL AGPLRTPLCG
    预测反应
    Cow: 85%, Horse: 93%, Human: 100%, Rat: 77%
    纯化方法
    Affinity purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human APEX2
    Top Product
    Discover our top product APEX2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    APEX2 (APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2))
    别名
    APEX2 (APEX2 产品)
    别名
    APE2 antibody, APEXL2 antibody, XTH2 antibody, ape2 antibody, apexl2 antibody, xth2 antibody, zgc:55889 antibody, C430040P13Rik antibody, apurinic/apyrimidinic endodeoxyribonuclease 2 antibody, APEX nuclease (apurinic/apyrimidinic endonuclease) 2 antibody, apurinic/apyrimidinic endodeoxyribonuclease 2 L homeolog antibody, apurinic/apyrimidinic endonuclease 2 antibody, APEX2 antibody, apex2 antibody, apex2.L antibody, Apex2 antibody
    背景
    Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

    Alias Symbols: APE2, XTH2, ZGRF2, APEXL2

    Protein Interaction Partner: UBC, PDE12, APP, NEDD4L, CCDC85B, NINL, HOOK2, PGR, CALCOCO2, TRIM37, EFEMP2, TRAF2, PCNA,

    Protein Size: 518
    基因ID
    27301
    NCBI登录号
    NM_014481, NP_055296
    UniProt
    Q9UBZ4
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