电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

ROBO3 抗体 (C-Term)

ROBO3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5515113
发货至: 中国
  • 抗原 See all ROBO3 抗体
    ROBO3 (Roundabout, Axon Guidance Receptor, Homolog 3 (ROBO3))
    抗原表位
    • 3
    • 3
    • 2
    • 1
    C-Term
    适用
    • 20
    • 5
    • 3
    • 3
    • 3
    • 1
    宿主
    • 15
    • 4
    • 4
    克隆类型
    • 21
    • 2
    多克隆
    标记
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ROBO3 antibody is un-conjugated
    应用范围
    • 14
    • 13
    • 5
    • 1
    Western Blotting (WB)
    序列
    HPSRSPSAQE PRGSCCPSNP DPDDRYYNEA GISLYLAQTA RGTAAPGEGP
    产品特性
    This is a rabbit polyclonal antibody against ROBO3. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human ROBO3
    Top Product
    Discover our top product ROBO3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    ROBO3 (Roundabout, Axon Guidance Receptor, Homolog 3 (ROBO3))
    别名
    ROBO3 (ROBO3 产品)
    别名
    HGPPS antibody, HGPS antibody, RBIG1 antibody, RIG1 antibody, CG14345 antibody, CT17158 antibody, Robo-3 antibody, Robo3 antibody, dRobo-3 antibody, DmelCG5423 antibody, CG5423 antibody, ROBO3 antibody, robo3 antibody, DKFZp468G0223 antibody, Rbig1 antibody, Rig-1 antibody, Rig1 antibody, Robo3a antibody, Robo3b antibody, cb503 antibody, roundabout guidance receptor 3 antibody, roundabout 3 antibody, robo3 antibody, roundabout guidance receptor 3 L homeolog antibody, roundabout, axon guidance receptor, homolog 3 (Drosophila) antibody, ROBO3 antibody, robo3 antibody, Robo3 antibody, LOC658818 antibody, robo3.L antibody
    背景
    This gene is a member of the Roundabout (ROBO) gene family that controls neurite outgrowth, growth cone guidance, and axon fasciculation. ROBO proteins are a subfamily of the immunoglobulin transmembrane receptor superfamily. SLIT proteins 1-3, a family of secreted chemorepellants, are ligands for ROBO proteins and SLIT/ROBO interactions regulate myogenesis, leukocyte migration, kidney morphogenesis, angiogenesis, and vasculogenesis in addition to neurogenesis. This gene, ROBO3, has a putative extracellular domain with five immunoglobulin (Ig)-like loops and three fibronectin (Fn) type III motifs, a transmembrane segment, and a cytoplasmic tail with three conserved signaling motifs: CC0, CC2, and CC3 (CC for conserved cytoplasmic). Unlike other ROBO family members, ROBO3 lacks motif CC1. The ROBO3 gene regulates axonal navigation at the ventral midline of the neural tube. In mouse, loss of Robo3 results in a complete failure of commissural axons to cross the midline throughout the spinal cord and the hindbrain. Mutations ROBO3 result in horizontal gaze palsy with progressive scoliosis (HGPPS), an autosomal recessive disorder characterized by congenital absence of horizontal gaze, progressive scoliosis, and failure of the corticospinal and somatosensory axon tracts to cross the midline in the medulla. Alternative transcript variants have been described but have not been experimentally validated.

    Alias Symbols: ROBO3,

    Protein Interaction Partner: CCDC57, LNX1, RBMX, MTUS2, Zswim8, APOA1, NEDD4L, UBC,

    Protein Size: 1386
    基因ID
    64221
    NCBI登录号
    NP_071765
    UniProt
    Q96MS0
You are here:
客服