Glucosylceramidase 抗体 (N-Term)
GLCM
适用: 小鼠, Pig, 兔, Cow, 大鼠, 犬, 豚鼠, 马, 人
WB
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all Glucosylceramidase (GLCM) products
- Glucosylceramidase (GLCM)
- 抗原表位
- N-Term
- 适用
- 小鼠, Pig, 兔, Cow, 大鼠, 犬, 豚鼠, 马, 人
- 宿主
- 兔
- 克隆类型
- 多克隆
- 应用范围
- Western Blotting (WB)
- 序列
- FSSPSREECP KPLSRVSIMA GSLTGLLLLQ AVSWASGARP CIPKSFGYSS
- 预测反应
- Cow: 75%, Dog: 75%, Guinea Pig: 75%, Horse: 75%, Human: 100%, Mouse: 75%, Pig: 79%, Rabbit: 75%, Rat: 75%
- 产品特性
- This is a rabbit polyclonal antibody against GLCM. It was validated on Western Blot.
- 纯化方法
- Affinity purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human GLCM
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Glucosylceramidase (GLCM)
- 别名
- GLCM (GLCM 产品)
- 背景
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This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
Alias Symbols: GBA, GC, GLUC,
Protein Interaction Partner: NUDCD1, UBC, ITCH, ATP6V1B1, SNCA, FBXO6, TCP1, CBL, NEDD4, PARK2, HSP90AA1, HSPA4, PSAP,
Protein Size: 536 - 基因ID
- 2629
- NCBI登录号
- XP_006711333
- UniProt
- P04062
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