AA407424 antibody, BB151133 antibody, Ssc1 antibody, elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1 antibody, ELOVL fatty acid elongase 1 antibody, Elovl1 antibody, ELOVL1 antibody
背景
ELOV1 is a condensing enzyme that catalyzes the synthesis of both saturated and monounsaturated very long chain fatty acids (VLCFAs). It exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. It is important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.
Alias Symbols: ELOVL1, SSC1, CGI-88,
Protein Interaction Partner: UBC, HSD17B12, CERS2, TECR, GLP1R, TWF2, PSMD10,