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MFN1 抗体 (AA 1-741)

Name: MFN1 抗体 (AA 1-741)
SKU: ABIN527615
Availability: OutOfStock

MFN1 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 3C9 unconjugated

Western Blot detection against Immunogen (107. (MFN1 抗体 (AA 1-741))

MFN1 monoclonal antibody (M04), clone 3C9. (MFN1 抗体 (AA 1-741))

MFN1 monoclonal antibody (M04), clone 3C9 Western Blot analysis of MFN1 expression in HeLa (MFN1 抗体 (AA 1-741))

Western blot analysis of MFN1 over-expressed 293 cell line, cotransfected with MFN1 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). (MFN1 抗体 (AA 1-741))

Western Blot analysis of MFN1 expression in transfected 293T cell line by MFN1 monoclonal antibody (M04), clone 3C9. (MFN1 抗体 (AA 1-741))

Detection limit for recombinant GST tagged MFN1 is 0. (MFN1 抗体 (AA 1-741))

ELISA

6 images

(14 references)

产品编号 ABIN527615

发货至: 中国

Datasheet as PDF

抗原 See all MFN1 抗体

MFN1 (Mitofusin 1 (MFN1))
抗原表位
16

7

7

7

6

4

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 1-741
适用
50

31

27

21

16

5

4

4

3

2

2

1

1

1

1
人
宿主
62

4

3

1
小鼠
Compatible Secondaries
克隆类型
59

11
单克隆
标记
33

4

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This MFN1 antibody is un-conjugated
应用范围
53

25

15

12

6

6

3

2

1

1
Western Blotting (WB), ELISA, RNA Interference (RNAi)

原理

Mouse monoclonal antibody raised against a full length recombinant MFN1.

序列

MAEPVSPLKH FVLAKKAITA IFDQLLEFVT EGSHFVEATY KNPELDRIAT EDDLVEMQGY KDKLSIIGEV LSRRHMKVAF FGRTSSGKSS VINAMLWDKV LPSGIGHITN CFLSVEGTDG DKAYLMTEGS DEKKSVKTVN QLAHALHMDK DLKAGCLVRV FWPKAKCALL RDDLVLVDSP GTDVTTELDS WIDKFCLDAD VFVLVANSES TLMNTEKHFF HKVNERLSKP NIFILNNRWD ASASEPEYME DVRRQHMERC LHFLVEELKV VNALEAQNRI FFVSAKEVLS ARKQKAQGMP ESGVALAEGF HARLQEFQNF EQIFEECISQ SAVKTKFEQH TIRAKQILAT VKNIMDSVNL AAEDKRHYSV EEREDQIDRL DFIRNQMNLL TLDVKKKIKE VTEEVANKVS CAMTDEICRL SVLVDEFCSE FHPNPDVLKI YKSELNKHIE DGMGRNLADR CTDEVNALVL QTQQEIIENL KPLLPAGIQD KLHTLIPCKK FDLSYNLNYH KLCSDFQEDI VFRFSLGWSS LVHRFLGPRN AQRVLLGLSE PIFQLPRSLA STPTAPTTPA TPDNASQEEL MITLVTGLAS VTSRTSMGII IVGGVIWKTI GWKLLSVSLT MYGALYLYER LSWTTHAKER AFKQQFVNYA TEKLRMIVSS TSANCSHQVK QQIATTFARL CQQVDITQKQ LEEEIARLPK EIDQLEKIQN NSKLLRNKAV QLENELENFT KQFLPSSNEE S

特异性

This antibody may cross react with MFN2 protein.

交叉反应

人

产品特性

Antibody Reactive Against Recombinant Protein.

免疫原

MFN1 (AAH40557, 1 a.a. ~ 741 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

克隆位点

3C9

亚型

IgG2a
anti-Mitofusin 1 (MFN1) (AA 1-234) antibody
MFN1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 1 (MFN1) (AA 651-741) antibody
MFN1 适用: 小鼠, 大鼠, 兔, 小鸡 WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 1 (MFN1) (AA 622-741) antibody
MFN1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 1 (MFN1) (AA 622-741) antibody
MFN1 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 1 (MFN1) (Internal Region) antibody
MFN1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 1 (MFN1) (AA 209-469) antibody
MFN1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4D11 unconjugated

anti-Mitofusin 1 (MFN1) (AA 745-756) antibody
MFN1 适用: 人, 兔, 犬, 马, 猴 IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated

anti-Mitofusin 1 (MFN1) (AA 622-741) antibody
MFN1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 1 (MFN1) (AA 1-227) antibody
MFN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Mitofusin 1 (MFN1) (AA 1-100) antibody
MFN1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

应用备注

Optimal working dilution should be determined by the investigator.

限制

仅限研究用
缓冲液

In 1x PBS, pH 7.4

注意事项

Aliquot to avoid repeated freezing and thawing.

储存条件

-20 °C

储存方法

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Chen, Chen, Wang, Tan, Zhu, Li, Han, Chen, Gao, Liu, Chen: "Mitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy." in: Autophagy, Vol. 12, Issue 4, pp. 689-702, (2016) (PubMed).

Baba, Kashiwagi, Arimitsu, Kogure, Edo, Maruyama, Nakao, Nakanishi, Kinoshita, Frohman, Yamamoto, Tani: "Phosphatidic acid (PA)-preferring phospholipase A1 regulates mitochondrial dynamics." in: The Journal of biological chemistry, Vol. 289, Issue 16, pp. 11497-511, (2014) (PubMed).

Yue, Chen, Liu, Yan, Chen, Feng, Yan, Wu, Du, Wang, Liu, Huang, Xia, Liu, Wang, Jin, Wang, Song, Hao, Chen: "A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30." in: Cell research, Vol. 24, Issue 4, pp. 482-96, (2014) (PubMed).

Shiba-Fukushima, Inoshita, Hattori, Imai: "Lysine 63-linked polyubiquitination is dispensable for Parkin-mediated mitophagy." in: The Journal of biological chemistry, Vol. 289, Issue 48, pp. 33131-6, (2014) (PubMed).

Takamura, Koyama, Matsuzaki, Yamada, Hattori, Miyata, Takemoto, Tohyama, Katayama: "TRAP1 controls mitochondrial fusion/fission balance through Drp1 and Mff expression." in: PLoS ONE, Vol. 7, Issue 12, pp. e51912, (2013) (PubMed).

Goller, Seibold, Kremmer, Voos, Kolanus: "Atad3 function is essential for early post-implantation development in the mouse." in: PLoS ONE, Vol. 8, Issue 1, pp. e54799, (2013) (PubMed).

Russell, Lamon, Boon, Wada, Güller, Brown, Chibalin, Zierath, Snow, Stepto, Wadley, Akimoto: "Regulation of miRNAs in human skeletal muscle following acute endurance exercise and short-term endurance training." in: The Journal of physiology, Vol. 591, Issue Pt 18, pp. 4637-53, (2013) (PubMed).

Ban-Ishihara, Ishihara, Sasaki, Mihara, Ishihara: "Dynamics of nucleoid structure regulated by mitochondrial fission contributes to cristae reformation and release of cytochrome c." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 29, pp. 11863-8, (2013) (PubMed).

Fülöp, Rajki, Katona, Szanda, Spät: "Extramitochondrial OPA1 and adrenocortical function." in: Molecular and cellular endocrinology, Vol. 381, Issue 1-2, pp. 70-9, (2013) (PubMed).

Lin, Lai, Lin, Lin, Wang, Lin, Lee, Wang, Chen: "Suppressor of cytokine signaling 6 (SOCS6) promotes mitochondrial fission via regulating DRP1 translocation." in: Cell death and differentiation, Vol. 20, Issue 1, pp. 139-53, (2012) (PubMed).

Shiba-Fukushima, Imai, Yoshida, Ishihama, Kanao, Sato, Hattori: "PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy." in: Scientific reports, Vol. 2, pp. 1002, (2012) (PubMed).

Bui, Gilady, Fitzsimmons, Benson, Lynes, Gesson, Alto, Strack, Scott, Simmen: "Rab32 modulates apoptosis onset and mitochondria-associated membrane (MAM) properties." in: The Journal of biological chemistry, Vol. 285, Issue 41, pp. 31590-602, (2010) (PubMed).

Zanna, Ghelli, Porcelli, Karbowski, Youle, Schimpf, Wissinger, Pinti, Cossarizza, Vidoni, Valentino, Rugolo, Carelli: "OPA1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion." in: Brain : a journal of neurology, Vol. 131, Issue Pt 2, pp. 352-67, (2008) (PubMed).

Holloway, Perry, Thrush, Heigenhauser, Dyck, Bonen, Spriet: "PGC-1alpha's relationship with skeletal muscle palmitate oxidation is not present with obesity despite maintained PGC-1alpha and PGC-1beta protein." in: American journal of physiology. Endocrinology and metabolism, Vol. 294, Issue 6, pp. E1060-9, (2008) (PubMed).
抗原

MFN1 (Mitofusin 1 (MFN1))

别名

MFN1 (MFN1 产品)

别名

mfn1 antibody, zgc:66150 antibody, mitofusin-1 antibody, MFN1 antibody, MFN2 antibody, hfzo1 antibody, hfzo2 antibody, 2310002F04Rik antibody, 6330416C07Rik antibody, D3Ertd265e antibody, HR2 antibody, mKIAA4032 antibody, Fzo1b antibody, mitofusin 1b antibody, mitofusin 1 antibody, mitofusin 1 S homeolog antibody, mfn1b antibody, MFN1 antibody, mfn1.S antibody, mfn1 antibody, Mfn1 antibody

背景

Full Gene Name: mitofusin 1
Synonyms: DKFZp762F247,FLJ20693,MGC41806,hfzo1,hfzo2

基因ID

55669