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FBXW7 抗体 (AA 599-707)

FBXW7 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D1 unconjugated
产品编号 ABIN527479
发货至: 中国
  • 抗原 See all FBXW7 抗体
    FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
    抗原表位
    • 15
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 599-707
    适用
    • 63
    • 35
    • 32
    • 16
    • 15
    • 14
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 52
    • 12
    小鼠
    克隆类型
    • 55
    • 9
    单克隆
    标记
    • 33
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This FBXW7 antibody is un-conjugated
    应用范围
    • 54
    • 24
    • 14
    • 13
    • 13
    • 11
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Mouse monoclonal antibody raised against a partial recombinant FBXW7.
    序列
    ADSTVKIWDI KTGQCLQTLQ GPNKHQSAVT CLQFNKNFVI TSSDDGTVKL WDLKTGEFIR NLVTLESGGS GGVVWRIRAS NTKLVCAVGS RNGTEETKLL VLDFDVDMK
    交叉反应
    产品特性
    Antibody Reactive Against Recombinant Protein.
    免疫原
    FBXW7 (NP_361014, 599 a.a. ~ 707 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    克隆位点
    3D1
    亚型
    IgG2a
    Top Product
    Discover our top product FBXW7 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    In 1x PBS, pH 7.4
    注意事项
    Aliquot to avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Hua, Ding, Yang: "Dysfunction of microRNA-32 regulates ubiquitin ligase FBXW7 in multiple myeloma disease." in: OncoTargets and therapy, Vol. 9, pp. 6573-6579, (2016) (PubMed).

    Yumimoto, Akiyoshi, Ueo, Sagara, Onoyama, Ueo, Ohno, Mori, Mimori, Nakayama: "F-box protein FBXW7 inhibits cancer metastasis in a non-cell-autonomous manner." in: The Journal of clinical investigation, Vol. 125, Issue 2, pp. 621-35, (2015) (PubMed).

    Yokobori, Yokoyama, Mogi, Endoh, Altan, Kosaka, Yamaki, Yajima, Tomizawa, Azuma, Onozato, Miyazaki, Tanaka, Kuwano: "FBXW7 mediates chemotherapeutic sensitivity and prognosis in NSCLCs." in: Molecular cancer research : MCR, Vol. 12, Issue 1, pp. 32-7, (2014) (PubMed).

    Lin, Hao, Nagata, Xu, Shang, Meng, Sato, Okuno, Varela, Ding, Garg, Liu, Yang, Yin, Shi, Jiang, Gu, Gong, Zhang, Xu, Kalid, Shacham, Ogawa, Wang, Koeffler: "Genomic and molecular characterization of esophageal squamous cell carcinoma." in: Nature genetics, Vol. 46, Issue 5, pp. 467-73, (2014) (PubMed).

    Enchev, Scott, da Fonseca, Schreiber, Monda, Schulman, Peter, Morris: "Structural basis for a reciprocal regulation between SCF and CSN." in: Cell reports, Vol. 2, Issue 3, pp. 616-27, (2012) (PubMed).

  • 抗原
    FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
    别名
    FBXW7 (FBXW7 产品)
    别名
    cdc4 antibody, AGO antibody, CDC4 antibody, FBW6 antibody, FBW7 antibody, FBX30 antibody, FBXO30 antibody, FBXW6 antibody, SEL-10 antibody, SEL10 antibody, hAgo antibody, hCdc4 antibody, 1110001A17Rik antibody, Cdc4 antibody, Fbw7 antibody, Fbwd6 antibody, Fbx30 antibody, Fbxo30 antibody, Fbxw6 antibody, F-box and WD repeat domain containing 7 antibody, F-box and WD-40 domain protein 7 antibody, Fbxw7 antibody, FBXW7 antibody, fbxw7 antibody
    背景
    Full Gene Name: F-box and WD repeat domain containing 7
    Synonyms: AGO,CDC4,DKFZp686F23254,FBW6,FBW7,FBX30,FBXO30,FBXW6,FLJ16457,SEL-10,SEL10
    基因ID
    55294
    NCBI登录号
    NM_033632
    途径
    Notch Signaling, EGFR Signaling Pathway
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