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RNF111 抗体 (AA 1-108)

RNF111 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 1C4 unconjugated
产品编号 ABIN527194
发货至: 中国
  • 抗原 See all RNF111 抗体
    RNF111 (Ring Finger Protein 111 (RNF111))
    抗原表位
    • 15
    • 8
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-108
    适用
    • 33
    • 32
    • 22
    宿主
    • 45
    • 3
    小鼠
    克隆类型
    • 47
    • 1
    单克隆
    标记
    • 16
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RNF111 antibody is un-conjugated
    应用范围
    • 19
    • 17
    • 13
    • 13
    • 4
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunofluorescence (IF), RNA Interference (RNAi)
    原理
    Mouse monoclonal antibody raised against a partial recombinant RNF111.
    序列
    MSQWTPEYNE LYTLKVDMKS EIPSDAPKTQ ESLKGILLHP EPIGAAKSFP AGVEMINSKV GNEFSHLCDD SQKQEKEMNG NQQEQEKSLV VRKKRKSQQA GPSYVQNC
    交叉反应
    产品特性
    Antibody Reactive Against Recombinant Protein.
    免疫原
    RNF111 (NP_060080, 1 a.a. ~ 108 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    克隆位点
    1C4
    亚型
    IgG2a
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    In 1x PBS, pH 7.4
    注意事项
    Aliquot to avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • van Cuijk, van Belle, Turkyilmaz, Poulsen, Janssens, Theil, Sabatella, Lans, Mailand, Houtsmuller, Vermeulen, Marteijn: "SUMO and ubiquitin-dependent XPC exchange drives nucleotide excision repair." in: Nature communications, Vol. 6, pp. 7499, (2015) (PubMed).

    Ma, Chen, Zhang, Yang, Wang, Yu: "RNF111-dependent neddylation activates DNA damage-induced ubiquitination." in: Molecular cell, Vol. 49, Issue 5, pp. 897-907, (2013) (PubMed).

    Erker, Neyret-Kahn, Seeler, Dejean, Atfi, Levy: "Arkadia, a novel SUMO-targeted ubiquitin ligase involved in PML degradation." in: Molecular and cellular biology, Vol. 33, Issue 11, pp. 2163-77, (2013) (PubMed).

    Poulsen, Hansen, Wagner, van Cuijk, van Belle, Streicher, Wikström, Choudhary, Houtsmuller, Marteijn, Bekker-Jensen, Mailand: "RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response." in: The Journal of cell biology, Vol. 201, Issue 6, pp. 797-807, (2013) (PubMed).

    Javelaud, van Kempen, Alexaki, Le Scolan, Luo, Mauviel: "Efficient TGF-?/SMAD signaling in human melanoma cells associated with high c-SKI/SnoN expression." in: Molecular cancer, Vol. 10, Issue 1, pp. 2, (2011) (PubMed).

    Koinuma, Shinozaki, Nagano, Ikushima, Horiguchi, Goto, Chano, Saitoh, Imamura, Miyazono, Miyazawa: "RB1CC1 protein positively regulates transforming growth factor-beta signaling through the modulation of Arkadia E3 ubiquitin ligase activity." in: The Journal of biological chemistry, Vol. 286, Issue 37, pp. 32502-12, (2011) (PubMed).

    Nagano, Koinuma, Miyazawa, Miyazono: "Context-dependent regulation of the expression of c-Ski protein by Arkadia in human cancer cells." in: Journal of biochemistry, Vol. 147, Issue 4, pp. 545-54, (2010) (PubMed).

    Nanjundan, Cheng, Zhang, Lahad, Kuo, Schmandt, Smith-McCune, Fishman, Gray, Mills: "Overexpression of SnoN/SkiL, amplified at the 3q26.2 locus, in ovarian cancers: a role in ovarian pathogenesis." in: Molecular oncology, Vol. 2, Issue 2, pp. 164-81, (2009) (PubMed).

    Levy, Howell, Das, Harkin, Episkopou, Hill: "Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation." in: Molecular and cellular biology, Vol. 27, Issue 17, pp. 6068-83, (2007) (PubMed).

  • 抗原
    RNF111 (Ring Finger Protein 111 (RNF111))
    别名
    RNF111 (RNF111 产品)
    背景
    Full Gene Name: ring finger protein 111
    Synonyms: ARK,DKFZp313E0731,DKFZp686H1966,DKFZp761D081,FLJ38008
    基因ID
    54778
    NCBI登录号
    NM_017610
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