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TFAM 抗体 (AA 1-246)

TFAM 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
产品编号 ABIN520832
发货至: 中国
  • 抗原 See all TFAM 抗体
    TFAM (Transcription Factor A, Mitochondrial (TFAM))
    抗原表位
    • 15
    • 13
    • 9
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-246
    适用
    • 56
    • 29
    • 25
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 84
    • 3
    小鼠
    克隆类型
    • 76
    • 11
    多克隆
    标记
    • 38
    • 9
    • 9
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TFAM antibody is un-conjugated
    应用范围
    • 67
    • 35
    • 26
    • 23
    • 16
    • 15
    • 14
    • 14
    • 14
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Mouse polyclonal antibody raised against a full-length human TFAM protein.
    序列
    MAFLRSMWGV LSALGRSGAE LCTGCGSRLR SPFSFVYLPR WFSSVLASCP KKPVSSYLRF SKEQLPIFKA QNPDAKTTEL IRRIAQRWRE LPDSKKKIYQ DAYRAEWQVY KEEISRFKEQ LTPSQIMSLE KEIMDKHLKR KAMTKKKELT LLGKPKRPRS AYNVYVAERF QEAKGDSPQE KLKTVKENWK NLSDSEKELY IQHAKEDETR YHNEMKSWEE QMIEVGRKDL LRRTIKKQRK YGAEEC
    交叉反应
    产品特性
    Antibody reactive against mammalian transfected lysate.
    免疫原
    TFAM (NP_003192.1, 1 a.a. ~ 246 a.a) full-length human protein.
    Top Product
    Discover our top product TFAM Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    In 1x PBS, pH 7.4
    注意事项
    Aliquot to avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Takeda, Hasegawa, Ueha, Sakakibara, Kawamoto, Minamikawa, Sakai, Komori: "Decreased mitochondrial copy numbers in oral squamous cell carcinoma." in: Head & neck, Vol. 38, Issue 8, pp. 1170-5, (2016) (PubMed).

    Morishita, Kawamoto, Hara, Onishi, Ueha, Minoda, Katayama, Takemori, Fukase, Kurosaka, Kuroda, Akisue: "AICAR induces mitochondrial apoptosis in human osteosarcoma cells through an AMPK-dependent pathway." in: International journal of oncology, Vol. 50, Issue 1, pp. 23-30, (2016) (PubMed).

    Akbari, Sykora, Bohr: "Slow mitochondrial repair of 5'-AMP renders mtDNA susceptible to damage in APTX deficient cells." in: Scientific reports, Vol. 5, pp. 12876, (2015) (PubMed).

    Akbari, Keijzers, Maynard, Scheibye-Knudsen, Desler, Hickson, Bohr: "Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair." in: DNA repair, Vol. 16, pp. 44-53, (2014) (PubMed).

    Gibellini, Pinti, Boraldi, Giorgio, Bernardi, Bartolomeo, Nasi, De Biasi, Missiroli, Carnevale, Losi, Tesei, Pinton, Quaglino, Cossarizza: "Silencing of mitochondrial Lon protease deeply impairs mitochondrial proteome and function in colon cancer cells." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 12, pp. 5122-35, (2014) (PubMed).

    Gispert, Parganlija, Klinkenberg, Dröse, Wittig, Mittelbronn, Grzmil, Koob, Hamann, Walter, Büchel, Adler, Hrabé de Angelis, Busch, Zell, Reichert, Brandt, Osiewacz, Jendrach, Auburger: "Loss of mitochondrial peptidase Clpp leads to infertility, hearing loss plus growth retardation via accumulation of CLPX, mtDNA and inflammatory factors." in: Human molecular genetics, Vol. 22, Issue 24, pp. 4871-87, (2013) (PubMed).

    Rolland, Motori, Memar, Hench, Frank, Winklhofer, Conradt: "Impaired complex IV activity in response to loss of LRPPRC function can be compensated by mitochondrial hyperfusion." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 32, pp. E2967-76, (2013) (PubMed).

    Holmström, Iglesias-Gutierrez, Zierath, Garcia-Roves: "Tissue-specific control of mitochondrial respiration in obesity-related insulin resistance and diabetes." in: American journal of physiology. Endocrinology and metabolism, Vol. 302, Issue 6, pp. E731-9, (2012) (PubMed).

    Aamann, Sorensen, Hvitby, Berquist, Muftuoglu, Tian, de Souza-Pinto, Scheibye-Knudsen, Wilson, Stevnsner, Bohr: "Cockayne syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 7, pp. 2334-46, (2010) (PubMed).

  • 抗原
    TFAM (Transcription Factor A, Mitochondrial (TFAM))
    别名
    TFAM (TFAM 产品)
    别名
    tcf6 antibody, mttf1 antibody, mttfa antibody, tcf6l1 antibody, tcf6l2 antibody, tcf6l3 antibody, mttfa-A antibody, xl-mtTFA antibody, MGC153358 antibody, zgc:153358 antibody, MTTF1 antibody, MTTFA antibody, TCF6 antibody, TCF6L1 antibody, TCF6L2 antibody, TCF6L3 antibody, AI661103 antibody, Hmgts antibody, mtTFA antibody, tsHMG antibody, Mttfa antibody, transcription factor A, mitochondrial antibody, transcription factor A, mitochondrial L homeolog antibody, TFAM antibody, tfam.L antibody, tfam antibody, Tfam antibody
    背景
    Full Gene Name: transcription factor A, mitochondrial
    Synonyms: MtTF1,TCF6,TCF6L1,TCF6L2,TCF6L3,mtTFA
    基因ID
    7019
    NCBI登录号
    NM_003201
    途径
    Chromatin Binding
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