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- 抗原 See all NBR1 抗体
- NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))
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抗原表位
- AA 2-96
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This NBR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 原理
- Mouse monoclonal antibody raised against a partial recombinant NBR1.
- 序列
- EPQVTLNVTF KNEIQSFLVS DPENTTWADI EAMVKVSFDL NTIQIKYLDE ENEEVSINSQ GEYEEALKMA VKQGNQLQMQ VHEGHHVVDE APPPV
- 交叉反应
- 人, 大鼠
- 产品特性
- Antibody Reactive Against Recombinant Protein.
- 免疫原
- NBR1 (NP_005890, 2 a.a. ~ 96 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- 克隆位点
- 6B11
- 亚型
- IgG1
- Top Product
- Discover our top product NBR1 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- In 1x PBS, pH 7.4
- 注意事项
- Aliquot to avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Peroxin Pex14p is the key component for coordinated autophagic degradation of mammalian peroxisomes by direct binding to LC3-II." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 20, Issue 1, pp. 36-49, (2015) (PubMed).
: "Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo. ..." in: Nature cell biology, Vol. 16, Issue 11, pp. 1069-79, (2014) (PubMed).
: "Brain region- and age-dependent dysregulation of p62 and NBR1 in a mouse model of Huntington's disease." in: Neurobiology of disease, Vol. 52, pp. 219-28, (2013) (PubMed).
: "NBR1 acts as an autophagy receptor for peroxisomes." in: Journal of cell science, Vol. 126, Issue Pt 4, pp. 939-52, (2013) (PubMed).
: "Molecular determinants of selective clearance of protein inclusions by autophagy." in: Nature communications, Vol. 3, pp. 1240, (2012) (PubMed).
: "Nbr1 is a novel inhibitor of ligand-mediated receptor tyrosine kinase degradation." in: Molecular and cellular biology, Vol. 30, Issue 24, pp. 5672-85, (2010) (PubMed).
: "Spred2 interaction with the late endosomal protein NBR1 down-regulates fibroblast growth factor receptor signaling." in: The Journal of cell biology, Vol. 187, Issue 2, pp. 265-77, (2009) (PubMed).
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Peroxin Pex14p is the key component for coordinated autophagic degradation of mammalian peroxisomes by direct binding to LC3-II." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 20, Issue 1, pp. 36-49, (2015) (PubMed).
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- 抗原
- NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))
- 别名
- NBR1 (NBR1 产品)
- 别名
- fa99f08 antibody, wu:fa99f08 antibody, MGC69008 antibody, NBR1 antibody, 1A1-3B antibody, M17S2 antibody, mKIAA0049 antibody, Ca125 antibody, RGD1311421 antibody, neighbor of brca1 gene 1a antibody, neighbor of BRCA1 gene 1 L homeolog antibody, NBR1, autophagy cargo receptor antibody, neighbor of Brca1 gene 1 antibody, nbr1a antibody, nbr1.L antibody, NBR1 antibody, Nbr1 antibody
- 背景
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Full Gene Name: neighbor of BRCA1 gene 1
Synonyms: 1A1-3B,KIAA0049,M17S2,MIG19 - 基因ID
- 4077
- NCBI登录号
- NM_005899
- 途径
- Autophagy
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