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- 抗原 See all CD19 抗体
- CD19 (CD19 Molecule (CD19))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD19 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 特异性
- The mouse monoclonal antibody 4G7 recognizes an extracellular epitope of human CD19.
- 交叉反应 (详细)
- Human
- 纯化方法
- Purified by protein-A affinity chromatography.
- 纯度
- > 95 % (by SDS-PAGE)
- 免疫原
- Human CCL (chronic lymphocytic leukemia) cells
- 克隆位点
- 4G7
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CD19 Primary Antibody
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- 应用备注
- Flow cytrometry: Recommended dilution: 1 μg/mL.
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Do not freeze.
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EGFR induces expression of IRF-1 via STAT1 and STAT3 activation leading to growth arrest of human cancer cells." in: International journal of cancer. Journal international du cancer, Vol. 122, Issue 2, pp. 342-9, (2007) (PubMed).
: "Down-regulation of MLL-AF9, MLL and MYC expression is not obligatory for monocyte-macrophage maturation in AML-M5 cell lines carrying t(9;11)(p22;q23)." in: Oncology reports, Vol. 15, Issue 1, pp. 207-11, (2005) (PubMed).
: "Phenotypic and functional deficiencies of monocyte-derived dendritic cells in systemic lupus erythematosus (SLE) patients." in: International immunology, Vol. 16, Issue 11, pp. 1595-604, (2004) (PubMed).
: "Improved thymopoietic potential in aviremic HIV infected individuals treated with HAART by intermittent IL-2 administration." in: AIDS, Vol. 17, Issue 11, pp. 1621-30, (2003) (PubMed).
: "Cytofluorographic identification of activated T-cell subpopulations in the semen of men with spinal cord injuries." in: Journal of andrology, Vol. 23, Issue 4, pp. 551-6, (2002) (PubMed).
: "Selective attraction of naive and memory B cells by dendritic cells." in: Journal of leukocyte biology, Vol. 70, Issue 4, pp. 633-41, (2001) (PubMed).
: "Triggering Fc alpha-receptor I (CD89) recruits neutrophils as effector cells for CD20-directed antibody therapy." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 10, pp. 5954-61, (2000) (PubMed).
: "Phenotypic and functional evidence for the expression of CD4 by hematopoietic stem cells isolated from human fetal liver." in: Blood, Vol. 89, Issue 4, pp. 1364-75, (1997) (PubMed).
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EGFR induces expression of IRF-1 via STAT1 and STAT3 activation leading to growth arrest of human cancer cells." in: International journal of cancer. Journal international du cancer, Vol. 122, Issue 2, pp. 342-9, (2007) (PubMed).
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- 抗原
- CD19 (CD19 Molecule (CD19))
- 别名
- CD19 (CD19 产品)
- 别名
- B4 antibody, CVID3 antibody, AW495831 antibody, CD19 antibody, CD19 molecule antibody, CD19 antigen antibody, CD19 antibody, Cd19 antibody
- 背景
- CD19 Molecule,CD19 is a transmembrane glycoprotein of Ig superfamily expressed by B cells from the time of heavy chain rearrangement until plasma cell differentiation. It forms a tetrameric complex with CD21 (complement receptor type 2), CD81 (TAPA-1) and Leu13. Together with BCR (B cell antigen receptor), this complex signals to decrease B cell treshold for activation by the antigen. Besides being signal-amplifying coreceptor for BCR, CD19 can also signal independently of BCR coligation and it turns out to be a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.,B4, Leu-12, CVID3
- 基因ID
- 930
- UniProt
- P15391
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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