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HLA-ABC 抗体 (FITC)

GMP Grade HLA-ABC 适用: 人, Baboon, Cynomolgus, 猕猴 FACS 宿主: 小鼠 Monoclonal W6-32 FITC
产品编号 ABIN5067847
发货至: 中国
  • 抗原 See all HLA-ABC 抗体
    HLA-ABC
    适用
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    人, Baboon, Cynomolgus, 猕猴
    宿主
    • 55
    • 9
    • 3
    小鼠
    克隆类型
    • 57
    • 9
    单克隆
    标记
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    This HLA-ABC antibody is conjugated to FITC
    应用范围
    • 52
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    • 1
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    Flow Cytometry (FACS)
    原理
    Anti-HLA-ABC FITC Antibody
    产品特性
    Clone W6/32 recognizes a cell surface 45 kD non-polymorphic epitope protein shared among products of the HLA-A, B, and C loci. HLA class I antigen associated with beta 2-microglobulin are expressed by all human nucleated cells and HLA-Class I down regulation occurs frequently in many cancers which might adversely affect the clinical course of cancer and the outcome of T-cell-based immunotherapy. HLA-Class I present specific foreign antigen to CD8+ T cells which play central role against infection, tumor and also generation of autoimmune diseases.
    纯化方法
    Purified
    纯度
    >95 %
    质量等级
    GMP Grade
    免疫原
    Human Leukocytes
    克隆位点
    W6-32
    亚型
    IgG2a, kappa
    Top Product
    Discover our top product HLA-ABC Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    2-8°C, Conjugated antibodies should never be frozen.
  • 抗原
    HLA-ABC
    别名
    HLA-ABC (HLA-ABC 产品)
    别名
    HLAA antibody, major histocompatibility complex, class I, A antibody, HLA-A antibody
    途径
    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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