HLA-ABC 抗体
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- 抗原 See all HLA-ABC 抗体
- HLA-ABC
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适用
- 人, Baboon, Cynomolgus, 猕猴
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This HLA-ABC antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 原理
- Anti-HLA-ABC Unconjugated Antibody
- 产品特性
- Clone W6/32 recognizes a cell surface 45 kD non-polymorphic epitope protein shared among products of the HLA-A, B, and C loci. HLA class I antigen associated with beta 2-microglobulin are expressed by all human nucleated cells and HLA-Class I down regulation occurs frequently in many cancers which might adversely affect the clinical course of cancer and the outcome of T-cell-based immunotherapy. HLA-Class I present specific foreign antigen to CD8+ T cells which play central role against infection, tumor and also generation of autoimmune diseases.
- 纯化方法
- Purified
- 纯度
- >95 %
- 质量等级
- GMP Grade
- 免疫原
- Human Leukocytes
- 克隆位点
- W6-32
- 亚型
- IgG2a, kappa
- Top Product
- Discover our top product HLA-ABC Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
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- 抗原
- HLA-ABC
- 别名
- HLA-ABC (HLA-ABC 产品)
- 别名
- HLAA antibody, major histocompatibility complex, class I, A antibody, HLA-A antibody
- 途径
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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